Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5411421 | 0.89 | DHODH (0.38) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL5414622 | 0.80 | TP53 (0.38) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL5366172 | 0.78 | PTGDR2 (0.53) | LMNAMAPTALDH1A1KDM4EDHODH | |
| SCHEMBL5418954 | 0.76 | LMNA (0.48) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL5398487 | 0.74 | PPARA (0.49) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL5415273 | 0.73 | PPARA (0.49) | LMNAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL5414629 | 0.72 | NPC1 (0.43) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL5364912 | 0.68 | KMT2A (0.67) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL5402842 | 0.67 | DHODH (0.62) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL5397042 | 0.66 | KMT2A (0.58) | LMNAMAPTALDH1A1KDM4EDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |