Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6525379 | 0.84 | AR (0.58) | ARGRIA2GRIA4 | |
| SCHEMBL5365095 | 0.80 | AR (0.65) | ARGRIA2GRIA4PDE9APDE1C | |
| SCHEMBL6466386 | 0.80 | AR (0.58) | ARGRIA2GRIA4SLC11A2 | |
| SCHEMBL5366353 | 0.80 | AR (0.60) | ARGRIA2GRIA4CYP11B2 | |
| SCHEMBL5358573 | 0.79 | AR (0.54) | ARGRIA2GRIA4MAPTLMNA | |
| SCHEMBL6466161 | 0.78 | AR (0.58) | ARGRIA2GRIA4PDE9APDE1C | |
| SCHEMBL5358210 | 0.76 | AR (0.47) | ARACSS2 | |
| SCHEMBL5362174 | 0.73 | AR (0.44) | AR | |
| SCHEMBL5362232 | 0.72 | AR (0.61) | ARGRIA2GRIA4CYP11B2KDM4E | |
| SCHEMBL6468889 | 0.71 | AR (0.86) | ARPDE9APDE1CCYP11B2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |