Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443825 | 0.88 | ALDH1A1 (0.54) | RAB9AALDH1A1SMN1; SMN2NPC1HTT | |
| SCHEMBL3781252 | 0.87 | ALDH1A1 (0.62) | MAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL5375275 | 0.86 | MAPT (0.48) | MAPTRAB9APRKCAPRKCDL3MBTL1 | |
| SCHEMBL828610 | 0.85 | TSHR (0.51) | MAPTALDH1A1PRKCAPRKCDL3MBTL1 | |
| SCHEMBL9458991 | 0.85 | TSHR (0.46) | RAB9AALDH1A1PRKCAPRKCDL3MBTL1 | |
| SCHEMBL6227200 | 0.83 | PRKCA (0.43) | MAPTRAB9AALDH1A1PRKCAPRKCD | |
| SCHEMBL3074456 | 0.83 | PRKCA (0.45) | MAPTRAB9AALDH1A1PRKCAPRKCD | |
| SCHEMBL1417774 | 0.82 | ALDH1A1 (0.64) | MAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL27899853 | 0.82 | ALDH1A1 (0.56) | MAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL5373336 | 0.82 | MAPT (0.48) | MAPTRAB9AL3MBTL1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194396-B1 | SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS | BASF AG (DE) | 2005-11-09 | — | — | EP | claimed |
| US-7208545-B1 | Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-24 | — | — | US | disclosed |