Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5366430 | 0.87 | KMT2A (0.46) | MAPTRAB9AKMT2AGAAHSD17B10 | |
| SCHEMBL27628287 | 0.87 | LMNA (0.55) | RAB9ANPC1HTTSMN1; SMN2LMNA | |
| SCHEMBL5375275 | 0.85 | MAPT (0.48) | MAPTRAB9AKMT2AGAAHSD17B10 | |
| SCHEMBL14690342 | 0.84 | RAB9A (0.61) | MAPTRAB9AKMT2AL3MBTL1NPC1 | |
| SCHEMBL570196 | 0.84 | RAB9A (0.61) | MAPTRAB9AKMT2AL3MBTL1NPC1 | |
| SCHEMBL7859273 | 0.84 | CA12 (0.53) | MAPTL3MBTL1CA12CA1CA2 | |
| SCHEMBL1787876 | 0.83 | RAB9A (0.54) | MAPTRAB9AKMT2AL3MBTL1NPC1 | |
| SCHEMBL1072030 | 0.83 | HPGD (0.50) | MAPTRAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL30395772 | 0.83 | HPGD (0.50) | MAPTRAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL5366424 | 0.82 | MAPT (0.46) | MAPTRAB9AKMT2AGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208545-B1 | Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-24 | — | — | US | claimed |
| EP-1194396-B1 | SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS | BASF AG (DE) | 2005-11-09 | — | — | EP | claimed |
| US-7208545-B1 | Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-24 | — | — | US | disclosed |