Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6757539 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL524857 | 0.84 | GPR3 (0.30) | — | |
| Bromide SCHEMBL7927972 | 0.81 | GPR3 (0.30) | — | |
| Iodide SCHEMBL7930604 | 0.81 | GPR3 (0.30) | — | |
| Hydrochloric Acid SCHEMBL5582101 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL15671584 | 0.80 | NPC1 (0.33) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL2276418 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL1471143 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL7553305 | 0.78 | — | — | |
| SCHEMBL6697516 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309678-B2 | Polyamide supported metallocene catalysts | FINA TECHNOLOGY, INC. (US) | 2007-12-18 | — | — | US | disclosed |
| US-7125937-B2 | Polyorganosilsesquioxane supported metallocene catalysts | FINA TECHNOLOGY, INC. (US) | 2006-10-24 | — | — | US | disclosed |
| EP-1687141-A1 | HIGH TENACITY AND TOUGHNESS IN METALLOCENE POLYPROPYLENE FILMS | FINA TECHNOLOGY, INC. (US) | 2006-08-09 | — | — | EP | disclosed |
| US-20060154809-A1 | Polyorganosilsesquioxane supported metallocene catalysts | FINA TECHNOLOGY, INC. | 2006-07-13 | — | — | US | disclosed |
| WO-2006057631-A1 | HIGH TENACITY AND TOUGHNESS IN METALLOCENE POLYPROPYLENE FILMS | FINA TECHNOLOGY, INC. (US) | 2006-06-01 | — | — | WO | disclosed |
| EP-1613665-A1 | SUPPORTED METALLOCENE CATALYSTS | FINA TECHNOLOGY, INC. (US) | 2006-01-11 | — | — | EP | disclosed |
| US-20050171307-A1 | Polyamide supported metallocene catalysts | RAUSCHER DAVID J (US) | 2005-08-04 | — | — | US | disclosed |
| US-20050106973-A1 | High tenacity and toughness in metallocene polypropylene films | FINA TECHNOLOGY, INC. | 2005-05-19 | — | — | US | disclosed |
| US-6878787-B2 | Polyamide supported metallocene catalysts | FINA TECHNOLOGY, INC. (US) | 2005-04-12 | — | — | US | disclosed |
| US-20050049372-A1 | POLYAMIDE SUPPORTED METALLOCENE CATALYSTS | FINA TECHNOLOGY, INC. | 2005-03-03 | — | — | US | disclosed |
| US-6855783-B2 | Supported metallocene catalysts | FINA TECHNOLOGY, INC. (US) | 2005-02-15 | — | — | US | disclosed |
| WO-2004092225-A1 | SUPPORTED METALLOCENE CATALYSTS | FINA TECHNOLOGY, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
| US-20040204310-A1 | Supported metallocene catalysts | FINA TECHNOLOGY, INC. | 2004-10-14 | — | — | US | disclosed |