Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6366868 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL524857 | 0.82 | GPR3 (0.30) | — | |
| Bromide SCHEMBL7927972 | 0.79 | GPR3 (0.30) | — | |
| Iodide SCHEMBL7930604 | 0.79 | GPR3 (0.30) | — | |
| Hydrochloric Acid SCHEMBL5367425 | 0.78 | NPC1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7101297 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL9070296 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL7106065 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL3685366 | 0.74 | — | — | |
| Diphenylmethane SCHEMBL8779570 | 0.74 | MAPT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243795-B1 | COPOLYMER PRODUCTION PROCESS | MITSUI CHEMICALS INC (JP) | 2012-09-19 | — | — | EP | disclosed |
| US-7915358-B2 | Copolymer, production process thereof, lubricating oil viscosity modifier, and lubricating oil composition | MITSUI CHEMICALS, INC. (JP) | 2011-03-29 | — | — | US | disclosed |
| EP-2243795-A1 | A COPOLYMER, THE MANUFACTURE METHOD FOR SAID COPOLYMER, A LUBRICATING OIL VISCOSITY ADJUSTING AGENT, AND A LUBRICATING OIL COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2010-10-27 | — | — | EP | disclosed |
| US-20090209721-A1 | Copolymer, production process thereof, lubricating oil viscosity modifier, and lubricating oil composition | MITSUI CHEMICALS, INC. | 2009-08-20 | — | — | US | disclosed |