Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | DKK1 | O94907 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18281466 | 0.90 | MAPK14 (0.36) | WDR5ALDH1A1LMNACNR1MAPK14 | |
| SCHEMBL20337613 | 0.87 | WDR5 (0.44) | WDR5ALDH1A1LMNADKK1TP53 | |
| SCHEMBL5375885 | 0.83 | LMNA (0.42) | WDR5ALDH1A1LMNALRRK2IRAK4 | |
| SCHEMBL18281430 | 0.81 | MAPK14 (0.46) | WDR5ALDH1A1LMNAMAPK14TP53 | |
| SCHEMBL5375882 | 0.79 | NPC1 (0.41) | WDR5ALDH1A1LMNALRRK2 | |
| SCHEMBL5329805 | 0.78 | WDR5 (0.39) | WDR5ALDH1A1LMNAMAPK14 | |
| SCHEMBL5303254 | 0.77 | MAPK14 (0.38) | WDR5ALDH1A1LMNAMAPK14 | |
| SCHEMBL5306661 | 0.76 | WDR5 (0.40) | WDR5ALDH1A1LMNA | |
| SCHEMBL18281441 | 0.76 | WDR5 (0.38) | WDR5ALDH1A1LMNATP53 | |
| SCHEMBL18281476 | 0.75 | WDR5 (0.52) | WDR5ALDH1A1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034282-A2 | DIARYL-IMIDAZOLE COMPOUNDS CONDENSED WITH A HETEROCYCLE AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |