Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 7/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311345 | 0.86 | WDR5 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5375885 | 0.81 | LMNA (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5367755 | 0.79 | WDR5 (0.38) | ALDH1A1LMNAWDR5LRRK2 | |
| SCHEMBL18281466 | 0.77 | MAPK14 (0.36) | ALDH1A1LMNAWDR5KDM4EHPGD | |
| SCHEMBL18281430 | 0.68 | MAPK14 (0.46) | NPC1RAB9AALDH1A1LMNAWDR5 | |
| Acetic Acid SCHEMBL4951340 | 0.67 | NQO2 (0.40) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| Acetic Acid SCHEMBL4952218 | 0.67 | ITGB3 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5308583 | 0.66 | LMNA (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5306345 | 0.66 | LMNA (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5363983 | 0.66 | MAPT (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034282-A2 | DIARYL-IMIDAZOLE COMPOUNDS CONDENSED WITH A HETEROCYCLE AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | claimed |
| EP-3302710-A1 | MOBILIZING AGENTS AND USES THEREFOR | The University of Queensland (AU) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016191811-A1 | MOBILIZING AGENTS AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2016-12-08 | — | — | WO | disclosed |