Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536803 | 1.00 | NOS2 (0.41) | NOS2MEN1KMT2AHPGDGAA | |
| SCHEMBL1822238 | 0.90 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL4204012 | 0.90 | MEN1 (0.30) | MEN1KMT2A | |
| Oxalic Acid SCHEMBL29039002 | 0.81 | NOS2 (0.47) | NOS2MEN1KMT2AHPGDGAA | |
| SCHEMBL2321562 | 0.76 | — | — | |
| SCHEMBL17688357 | 0.76 | — | — | |
| SCHEMBL5771317 | 0.76 | — | — | |
| SCHEMBL890174 | 0.76 | — | — | |
| SCHEMBL11666409 | 0.75 | — | — | |
| Bromide SCHEMBL6143076 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2405860-B1 | OPHTHALMOLOGICAL COMPOSITION AND OPHTHALMOLOGICAL LENS | ZEISS CARL MEDITEC AG (DE) | 2013-09-25 | — | — | EP | disclosed |
| EP-2199834-B1 | Ophthalmological composition and ophthalmologic lens | ZEISS CARL MEDITEC AG (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-2225293-B1 | COPOLYMER AND OPHTHALMOLOGICAL COMPOSITION | ZEISS CARL MEDITEC AG (DE) | 2012-02-08 | — | — | EP | disclosed |
| US-20110028667-A1 | Copolymer and Ophthalmological Composition | *ACRI.TEC GMBH (DE) | 2011-02-03 | — | — | US | disclosed |
| EP-2225293-A2 | COPOLYMER AND OPHTHALMOLOGICAL COMPOSITION | *Acri. Tec GmbH (DE) | 2010-09-08 | — | — | EP | disclosed |
| EP-2199834-A1 | Ophthalmological composition and ophthalmologic lens | *Acri. Tec GmbH (DE) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009074520-A2 | COPOLYMER AND OPHTHALMOLOGICAL COMPOSITION | *ACRI.TEC GMBH (DE) | 2009-06-18 | — | — | WO | disclosed |