SCHEMBL5368019

SCHEMBL5368019

CCCOc1nc(Cl)nc(OCCC)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.41
POLB P06746 2/20 0.34
LMNA P02545 2/20 0.33
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 3/20 0.32
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
CSNK2A1 P68400 2/20 0.32
ITGB1 P05556 1/20 0.31
ITGA4 P13612 1/20 0.31
MAPK1 P28482 1/20 0.31
ENPP1 P22413 1/20 0.31
KDM4E B2RXH2 1/20 0.31
NFKB1 P19838 1/20 0.31
TLR8 Q9NR97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1370622 0.95 ALDH1A1 (0.38) PDE10APOLBLMNAALDH1A1ALOX15
SCHEMBL15247491 0.87 PDE10A (0.38) PDE10A
SCHEMBL632364 0.87 PDE10A (0.39) PDE10APOLBLMNAALDH1A1TSHR
SCHEMBL6051629 0.86 RAB9A (0.41) POLBLMNAHSD17B10NPC1CYP1A2
SCHEMBL17486055 0.83 NR5A1 (0.40) LMNAALDH1A1TSHRTP53GAA
SCHEMBL11390156 0.83 NR5A1 (0.40) LMNAALDH1A1TSHRTP53GAA
SCHEMBL11395631 0.83 NR5A1 (0.40) LMNAALDH1A1TSHRTP53GAA
SCHEMBL11387091 0.83 NR5A1 (0.40) LMNAALDH1A1TSHRTP53GAA
SCHEMBL11391229 0.83 NR5A1 (0.40) LMNAALDH1A1TSHRTP53GAA
SCHEMBL1318906 0.82 RAB9A (0.41) POLBLMNAALDH1A1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023181581-A1 DERIVATIZING COMPOSITION FOR MASS SPECTROMETRY, DERIVATIZATION KIT FOR MASS SPECTROMETRY, MASS SPECTROMETRIC METHOD FOR BIOLOGICAL COMPONENT, AND METHOD FOR PREPARING SAMPLE FOR USE IN MASS SPECTROMETRY 株式会社トクヤマ 2023-09-28 WO disclosed
EP-2899221-B1 METHOD FOR MANUFACTURING POLYROTAXANE SUMITOMO SEIKA CHEMICALS (JP) 2017-08-16 EP disclosed
US-9487630-B2 Method for manufacturing polyrotaxane SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2016-11-08 US disclosed
US-20150240036-A1 METHOD FOR MANUFACTURING POLYROTAXANE ASM INC. (JP) 2015-08-27 US disclosed
EP-2899221-A1 METHOD FOR MANUFACTURING POLYROTAXANE Sumitomo Seika Chemicals Co., Ltd. (JP) 2015-07-29 EP disclosed
US-7291645-B2 Phenylalanine derivatives as alpha 4 integrin inhibitors ELAN PHARMACEUTICALS, INC. (US) 2007-11-06 US disclosed
EP-1669351-A2 Method for preserving quaternary ammonium salt Tokuyama Corporation (JP) 2006-06-14 EP disclosed
US-7015216-B2 Heteroaryl-β-alanine derivatives as alpha 4 integrin inhibitors ELAN PHARMACEUTICALS, INC. (US) 2006-03-21 US disclosed
EP-1178043-B1 METHOD FOR STORING QUATERNARY AMMONIUM SALT TOKUYAMA CORP (JP) 2005-12-28 EP disclosed
CN-1196686-C Method for storing quaternary ammonium salt TOKUYAMA CORP (JP) 2005-04-13 CN disclosed
US-6348463-B1 Phenylalanine derivatives CELLTECH THERAPEUTICS LIMITED (GB) 2002-02-19 US disclosed
EP-1178043-A1 METHOD FOR STORING QUATERNARY AMMONIUM SALT TOKUYAMA CORPORATION (JP) 2002-02-06 EP disclosed
WO-2002008222-A2 HETEROARYL-β-ALANINE DERIVATIVES AS ALPHA 4 INTEGRIN INHIBITORS ELAN PHARMACEUTICALS, INC. (US) 2002-01-31 WO disclosed
WO-2002008206-A1 3-AMINO-2-(4-AMINOCARBONYLOXY)PHENYL-PROPIONIC ACID DERIVATIVES AS ALPHA-4- INTEGRIN INHIBITORS ELAN PHARMACEUTICALS, INC. (US) 2002-01-31 WO disclosed
EP-1117657-A1 PHENYLALANINE DERIVATIVES AS ALPHA 4 INTEGRIN INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 2001-07-25 EP disclosed
EP-1085000-A1 PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE AND CONDENSING AGENT COMPRISING QUATERNARY AMMONIUM SALT TOKUYAMA CORPORATION (JP) 2001-03-21 EP disclosed
WO-2000018759-A1 PHENYLALANINE DERIVATIVES AS ALPHA 4 INTEGRIN INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 2000-04-06 WO disclosed
US-5859243-A AMINOSILICONES HAVING PYRIMIDINYL GROUPS BOUND TO THE AMINO GROUPS; USED TO GEL SILICONE OIL OR TO INCREASE THE VISCOSITY STABLY AND HOMOGENEOUSLY; BASES FOR COSMETICS, DRUGS, INDUSTRIAL MATERIAL; FEEL; TEXTURE CHIBA FLOUR MILLING CO., LTD. (JP) 1999-01-12 US disclosed
US-5712391-A POLYSILOXANES MODIFIED WITH TRIAZINE GROUPS AND DIAMINE COMPOUNDS FOR COSMETICS CHIBA FLOUR MILLING CO., LTD. (JP) 1998-01-27 US disclosed
EP-0751170-A2 Silicone derivatives, their production and use Chiba Flour Milling Co., Ltd. (JP) 1997-01-02 EP disclosed