Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 10/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5378511 | 0.90 | AKT1 (0.39) | AKT1CDK2PREPFAPTAS1R3 | |
| SCHEMBL5362652 | 0.89 | AKT1 (0.41) | AKT1CDK2PREPFAPTAS1R3 | |
| SCHEMBL14425292 | 0.70 | ACHE (0.45) | KDM1AHDAC4 | |
| SCHEMBL5368483 | 0.70 | ACHE (0.45) | KDM1AHDAC4 | |
| SCHEMBL5368190 | 0.68 | EPHX2 (0.52) | KDM1A | |
| SCHEMBL2859970 | 0.66 | PREP (0.55) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2860724 | 0.64 | PREP (0.55) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2860717 | 0.64 | TAS1R3 (0.58) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2863465 | 0.63 | TAS1R3 (0.57) | PREPFAPTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2863458 | 0.63 | TAS1R3 (0.53) | PREPFAPTAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259157-B2 | N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B Antagonists | MERCK & CO., INC. (US) | 2007-08-21 | — | — | US | disclosed |