SCHEMBL5368535

SCHEMBL5368535

O[C@@H]1[C@H](CF)C[C@@H](n2cnc3c(Cl)ncnc32)[C@@H]1O

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AHCY P23526 7/20 0.58
ADORA2B P29275 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11162107 0.89 AHCY (0.73) AHCYADORA2B
SCHEMBL11162110 0.89 AHCY (0.73) AHCYADORA2B
SCHEMBL11162105 0.89 AHCY (0.73) AHCYADORA2B
SCHEMBL17889874 0.89 AHCY (0.73) AHCYADORA2B
SCHEMBL1799636 0.89 AHCY (0.73) AHCYADORA2B
SCHEMBL5364502 0.87 AHCY (0.60) AHCYADORA2B
SCHEMBL5366317 0.84 AHCY (0.52) AHCYADORA2B
SCHEMBL26382100 0.83 AHCY (0.71) AHCYADORA2B
SCHEMBL10172069 0.79 AHCY (0.53) AHCYADORA2B
SCHEMBL5381338 0.78 ADORA3 (0.59) ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7265111-B2 Adenosine analogues and their use as pharmaceutical agents SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2007-09-04 US claimed
US-20040127434-A1 Novel adenosine analogues and their use as pharmaceutical agents SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2004-07-01 US claimed
EP-1375508-A1 N6-substituted adenosine analogues and their use as pharmaceutical agents Aventis Pharma Deutschland GmbH (DE) 2004-01-02 EP claimed
US-7265111-B2 Adenosine analogues and their use as pharmaceutical agents SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2007-09-04 US disclosed
US-20040127434-A1 Novel adenosine analogues and their use as pharmaceutical agents SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2004-07-01 US disclosed
EP-1375508-A1 N6-substituted adenosine analogues and their use as pharmaceutical agents Aventis Pharma Deutschland GmbH (DE) 2004-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040127434-A1 Novel adenosine analogues and their use as pharmaceutical agents ADORA1, ADORA2A, ADORA2B AHCY 1110/4885ADORA2B 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.