Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 20/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313050 | 0.90 | CCR1 (0.43) | CCR1CYP2C19KCNH2 | |
| SCHEMBL5312337 | 0.83 | CCR1 (0.48) | CCR1CYP2C19KCNH2 | |
| SCHEMBL5373128 | 0.83 | CCR1 (0.46) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4454469 | 0.82 | CCR1 (0.62) | CCR1CYP2C19KCNH2 | |
| SCHEMBL5450338 | 0.75 | CCR1 (0.54) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4015802 | 0.75 | CCR1 (0.60) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4452522 | 0.72 | CCR1 (0.66) | CCR1CYP2C19KCNH2 | |
| SCHEMBL5362249 | 0.72 | CCR1 (0.39) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4308192 | 0.71 | CCR1 (0.46) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4565941 | 0.71 | CCR1 (0.55) | CCR1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044804-A2 | PIPERIDINE DERIVATIVES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-04-19 | — | — | WO | disclosed |