Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 16/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310532 | 0.91 | F10 (0.38) | CCR1F10KCNH2TACR1SLC6A4 | |
| SCHEMBL5373128 | 0.87 | CCR1 (0.46) | CCR1KCNH2CYP2C19 | |
| SCHEMBL5313190 | 0.85 | CCR1 (0.37) | CCR1F10KCNH2TACR1SLC6A4 | |
| SCHEMBL5314510 | 0.82 | HSD11B1 (0.48) | CCR1F10CYP2C19 | |
| SCHEMBL5312345 | 0.81 | HSD11B1 (0.49) | CCR1F10CYP2C19 | |
| SCHEMBL5308835 | 0.81 | CCR1 (0.40) | CCR1F10CYP2C19 | |
| SCHEMBL5313011 | 0.80 | ALDH1A1 (0.49) | CCR1F10CYP2C19 | |
| SCHEMBL5381831 | 0.80 | HSD11B1 (0.39) | CCR1F10CYP2C19 | |
| SCHEMBL5307882 | 0.80 | OPRM1 (0.43) | CCR1 | |
| SCHEMBL4018625 | 0.79 | CCR1 (0.53) | CCR1KCNH2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044804-A2 | PIPERIDINE DERIVATIVES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-04-19 | — | — | WO | disclosed |