Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 19/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5373128 | 0.89 | CCR1 (0.46) | CCR1CYP2C19KCNH2 | |
| SCHEMBL5313050 | 0.87 | CCR1 (0.43) | CCR1CYP2C19KCNH2 | |
| SCHEMBL5307882 | 0.84 | OPRM1 (0.43) | CCR1OPRM1OPRD1OPRK1 | |
| SCHEMBL5368732 | 0.83 | CCR1 (0.42) | CCR1CYP2C19KCNH2 | |
| SCHEMBL5450338 | 0.82 | CCR1 (0.54) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4015802 | 0.82 | CCR1 (0.60) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4452507 | 0.77 | CCR1 (0.71) | CCR1CYP2C19KCNH2 | |
| SCHEMBL4565941 | 0.77 | CCR1 (0.55) | CCR1CYP2C19KCNH2 | |
| SCHEMBL5313190 | 0.77 | CCR1 (0.37) | CCR1KCNH2SLC6A4 | |
| SCHEMBL5362249 | 0.76 | CCR1 (0.39) | CCR1CYP2C19KCNH2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044804-A2 | PIPERIDINE DERIVATIVES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-04-19 | — | — | WO | disclosed |