Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11506428 | 0.87 | SIGMAR1 (0.53) | TACR1SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL8014785 | 0.85 | TACR1 (0.65) | TACR1GNAI3GNAI1HTR1A | |
| SCHEMBL8913882 | 0.82 | TACR1 (0.57) | TACR1HTR1A | |
| SCHEMBL2420417 | 0.80 | HTR1A (0.62) | SIGMAR1HTR1A | |
| SCHEMBL11509359 | 0.79 | TACR1 (0.58) | TACR1HTR1A | |
| SCHEMBL10990821 | 0.79 | HTR1A (0.62) | TACR1GNAI3GNAO1GNAI1HTR1A | |
| Hydrochloric Acid SCHEMBL27465011 | 0.78 | HTR1A (0.60) | SIGMAR1HTR1A | |
| SCHEMBL7376521 | 0.77 | SIGMAR1 (0.85) | TACR1SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL14229118 | 0.77 | L3MBTL1 (0.52) | TACR1SIGMAR1HTR1A | |
| SCHEMBL7379352 | 0.76 | TACR1 (0.49) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |
| WO-1994013646-A1 | N,N-DIACYLPIPERAZINE TACHYKININ ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | disclosed |