⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9230410 | 0.72 | — | — | |
| SCHEMBL6026848 | 0.71 | GRIN2D (0.39) | — | |
| SCHEMBL68868 | 0.61 | — | — | |
| SCHEMBL7570194 | 0.57 | — | — | |
| SCHEMBL24699888 | 0.56 | — | — | |
| SCHEMBL28104 | 0.56 | GRIN2D (0.55) | — | |
| SCHEMBL891560 | 0.56 | — | — | |
| SCHEMBL191884 | 0.56 | GRIN2D (0.41) | — | |
| SCHEMBL65160 | 0.56 | — | — | |
| SCHEMBL191883 | 0.56 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129331-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES | RND PHARMACEUTICALS, INC. (US) | 2007-06-07 | — | — | US | claimed |
| EP-1737471-A2 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF LIPOPHILIC, SILICON-SUBSTITUTED, CYCLOOXYGENASE-2 SELECTIVE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND DERIVATIVES | RND Pharmaceuticals (US) | 2007-01-03 | — | — | EP | claimed |
| EP-1558654-A4 | NOVEL COPOLYMER, PHOTORESIST COMPOSITIONS THEREOF AND DEEP UV BILAYER SYSTEM THEREOF | FUJIFILM ELECTRONIC MATERIALS (US) | 2006-04-05 | — | — | EP | claimed |
| WO-2005102358-A2 | SILICONE-SUBSTITUTED COX-2 SELECTIVE INHIBITORS | RND PHARMACEUTICALS (US) | 2005-11-03 | — | — | WO | claimed |
| EP-1558654-A2 | NOVEL COPOLYMER, PHOTORESIST COMPOSITIONS THEREOF AND DEEP UV BILAYER SYSTEM THEREOF | Fujifilm Electronic Materials USA, Inc. (US) | 2005-08-03 | — | — | EP | claimed |
| US-6916543-B2 | Copolymer, photoresist compositions thereof and deep UV bilayer system thereof | ARCH SPECIALTY CHEMICALS, INC. (US) | 2005-07-12 | — | — | US | claimed |
| US-20040137362-A1 | Novel copolymer, photoresist compositions thereof and deep UV bilayer system thereof | ARCH SPECIALTY CHEMICALS, INC. | 2004-07-15 | — | — | US | claimed |
| WO-2004050665-A1 | SILICON COMPOUNDS | AMEDIS PHARMACEUTICALS LTD. (GB) | 2004-06-17 | — | — | WO | claimed |
| WO-2004050666-A1 | SILICON COMPOUNDS USEFUL IN CANCER THERAPY | AMEDIS PHARMACEUTICALS LTD. (GB) | 2004-06-17 | — | — | WO | claimed |
| WO-2004040371-A2 | NOVEL COPOLYMER AND PHOTORESIST COMPOSITIONS THEREOF | ARCH SPECIALTY CHEMICALS, INC. (US) | 2004-05-13 | — | — | WO | claimed |
| US-7081537-B2 | Process for the electrophilic substitution of thiazolidines or oxazolidines | Consortium für elektrochemische Industrie GmbH (DE) | 2006-07-25 | — | — | US | disclosed |
| US-20060030732-A1 | Process for cleaving thiazolidines | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2006-02-09 | — | — | US | disclosed |
| US-6916543-B2 | Copolymer, photoresist compositions thereof and deep UV bilayer system thereof | ARCH SPECIALTY CHEMICALS, INC. (US) | 2005-07-12 | — | — | US | disclosed |
| US-20040171840-A1 | Process for the electrophilic substitution of thiazolidines or oxazolidines | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2004-09-02 | — | — | US | disclosed |
| EP-1452529-A1 | PRocess for an electrophilic substitution of thiazolidines or oxazolidines | Consortium für elektrochemische Industrie GmbH (DE) | 2004-09-01 | — | — | EP | disclosed |
| US-20040137362-A1 | Novel copolymer, photoresist compositions thereof and deep UV bilayer system thereof | ARCH SPECIALTY CHEMICALS, INC. | 2004-07-15 | — | — | US | disclosed |
| WO-2004050665-A1 | SILICON COMPOUNDS | AMEDIS PHARMACEUTICALS LTD. (GB) | 2004-06-17 | — | — | WO | disclosed |
| US-4957989-A | ANTIFOULING AGENT FOR SHIP BOTTOMS, NONTOXIC | TOSHIBA SILICONE CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |