Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.47 |
| ▸ | HTR6 | P50406 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5378982 | 0.89 | KDM4E (0.49) | KDM4EHSD17B10ALDH1A1ALOX15MTNR1A | |
| SCHEMBL5371635 | 0.89 | KDM4E (0.49) | KDM4EHSD17B10ALDH1A1ALOX15MTNR1A | |
| SCHEMBL5329102 | 0.85 | KDM4E (0.46) | KDM4EHSD17B10ALDH1A1ALOX15MTNR1A | |
| SCHEMBL5373851 | 0.85 | HSD17B10 (0.46) | KDM4EHSD17B10ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL5333912 | 0.84 | KDM4E (0.48) | KDM4EHSD17B10ALDH1A1ALOX15MTNR1A | |
| SCHEMBL5379284 | 0.84 | ALDH1A1 (0.46) | KDM4EHSD17B10ALDH1A1ALOX15HTR6 | |
| SCHEMBL5375330 | 0.84 | MPO (0.52) | KDM4EALDH1A1HTR6HPGDHTR1A | |
| SCHEMBL6925863 | 0.80 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1ALOX15MTNR1A | |
| SCHEMBL1429039 | 0.75 | AHR (0.49) | KDM4EHSD17B10ALDH1A1ALOX15MTNR1A | |
| SCHEMBL5360266 | 0.75 | HSD17B10 (0.46) | KDM4EHSD17B10ALDH1A1HTR6HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |