Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333912 | 0.91 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10ALOX15MTNR1A | |
| SCHEMBL5332260 | 0.85 | POLB (0.44) | KDM4EALDH1A1HSD17B10HTR6MEN1 | |
| SCHEMBL5334148 | 0.85 | POLB (0.44) | KDM4EALDH1A1HSD17B10ALOX15HTR6 | |
| SCHEMBL5331577 | 0.85 | MPO (0.48) | KDM4EALDH1A1ACHEHTR6L3MBTL1 | |
| SCHEMBL5371635 | 0.85 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10ALOX15MTNR1A | |
| SCHEMBL5369909 | 0.85 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10ALOX15MTNR1A | |
| SCHEMBL5378982 | 0.85 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10ALOX15MTNR1A | |
| SCHEMBL5329097 | 0.85 | DRD2 (0.52) | KDM4EALDH1A1HTR6MEN1KMT2A | |
| SCHEMBL6925863 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10ALOX15MTNR1A | |
| SCHEMBL5313708 | 0.77 | HTR6 (0.67) | KDM4EALDH1A1HSD17B10MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |