Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NMT2 | O60551 | 1/20 | 0.44 |
| ▸ | NMT1 | P30419 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22438915 | 0.83 | MEN1 (0.65) | MAOBMEN1HSP90AA1KMT2ANR1H4 | |
| SCHEMBL8247860 | 0.81 | KDM4E (0.57) | MEN1KMT2ALMNAALDH1A1CYP1A2 | |
| SCHEMBL14280106 | 0.80 | MAOB (0.58) | MAOBNR1H4LMNAL3MBTL1ALOX5 | |
| Hydrochloric Acid SCHEMBL2770099 | 0.79 | KDM4E (0.55) | LMNAALDH1A1CYP1A2HIF1AMAPT | |
| SCHEMBL5035385 | 0.78 | MAOB (0.57) | MAOBKMT2A | |
| Hydrochloric Acid SCHEMBL26633553 | 0.78 | MAOB (0.56) | MAOBNR1H4LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL28256912 | 0.77 | MAOB (0.65) | MAOBMEN1HSP90AA1KMT2ANR1H4 | |
| SCHEMBL7911106 | 0.77 | ALDH1A1 (0.55) | MAOBMEN1HSP90AA1KMT2ANR1H4 | |
| SCHEMBL1488776 | 0.77 | MEN1 (0.63) | MAOBMEN1HSP90AA1KMT2ANR1H4 | |
| SCHEMBL384341 | 0.77 | MAOB (0.78) | MAOBL3MBTL1CYP2C19MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294718-B2 | Synthesis of a 4-methylthiazole-4(S)-carboxylic acid compound | GENZYME CORPORATION (US) | 2007-11-13 | — | — | US | disclosed |
| US-20050209462-A1 | Synthesis of benzimidate from benzoic acid | GENZYME CORPORATION (US) | 2005-09-22 | — | — | US | disclosed |
| EP-1506162-A2 | SYNTHESIS OF BENZONITRILES AND BENZIMIDATES | Genzyme Corporation (US) | 2005-02-16 | — | — | EP | disclosed |
| US-6846958-B2 | Synthesis of benzimidate from benzoic acid | GENZYME CORPORATION (US) | 2005-01-25 | — | — | US | disclosed |
| US-20030236426-A1 | Synthesis of benzimidate from benzoic acid | GENZYME CORPORATION | 2003-12-25 | — | — | US | disclosed |
| WO-2003097582-A2 | SYNTHESIS OF BENZONITRILES AND BENZIMIDATES | GENZYME CORPORATION (US) | 2003-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209462-A1 | Synthesis of benzimidate from benzoic acid | FTH1, CISD2, CISD1 | MAOB 1387/4885MEN1 755/4885HSP90AA1 1597/4885 |
| US-20030236426-A1 | Synthesis of benzimidate from benzoic acid | FTH1, CISD2, CISD1 | MAOB 1387/4885MEN1 755/4885HSP90AA1 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.