SCHEMBL537029

SCHEMBL537029

N=C(N)c1ccc(C(N)=O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
PLAU P00749 2/20 0.59
MASP2 O00187 1/20 0.59
THPO P40225 1/20 0.59
F2 P00734 7/20 0.59
PRSS1 P07477 4/20 0.59
PRSS3 P35030 4/20 0.59
ST14 Q9Y5Y6 3/20 0.59
PRSS2 P07478 3/20 0.59
TMPRSS6 Q8IU80 1/20 0.58
APEX1 P27695 1/20 0.56
F10 P00742 4/20 0.55
CYP2C19 P33261 2/20 0.55
HSD17B10 Q99714 2/20 0.55
BLM P54132 2/20 0.55
F12 P00748 1/20 0.55
F7 P08709 1/20 0.55
F3 P13726 1/20 0.55
PKM P14618 1/20 0.55
POLB P06746 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8652339 0.97 F2 (0.61) LMNAPLAUMASP2THPOF2
Hydrochloric Acid SCHEMBL1483999 0.97 F2 (0.61) LMNAPLAUMASP2THPOF2
Acetic Acid SCHEMBL5901032 0.91 NQO2 (0.61) LMNAPLAUMASP2THPOF2
Hydrochloric Acid SCHEMBL8994023 0.89 PARP15 (0.59) LMNAPLAUMASP2THPOF2
SCHEMBL537030 0.85 LMNA (0.77) LMNAPLAUMASP2THPOF2
Terephthalamide SCHEMBL23774 0.85 PARP1 (0.71) LMNACYP2C19HSD17B10BLMPOLB
Terephthalamide SCHEMBL15328883 0.82 PARP1 (0.67) LMNACYP2C19HSD17B10BLMPOLB
Terephthalamide SCHEMBL11512422 0.82 PARP1 (0.67) LMNACYP2C19HSD17B10BLMPOLB
Terephthalamide SCHEMBL7508927 0.82 PARP1 (0.67) LMNACYP2C19HSD17B10BLMPOLB
Terephthalamide SCHEMBL1906838 0.82 PARP1 (0.67) LMNACYP2C19HSD17B10BLMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 520 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119836101-A Perovskite solar cell based on diamine molten salt surface modification and preparation method thereof 东方电气长三角(杭州)创新研究院有限公司 2025-04-15 CN claimed
CN-118513038-A Hydrofining catalyst and preparation method and application thereof 中国石油化工股份有限公司 2024-08-20 CN claimed
EP-2796112-B2 Degradable implantable medical devices ELIXIR MEDICAL CORP (US) 2023-08-09 EP claimed
WO-2022217521-A1 COVALENT BOND-LINKED TIO2@CTF‑PY HETEROJUNCTION MATERIAL, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 苏州大学 2022-10-20 WO claimed
CN-112321782-B Crystalline covalent triazine organic framework material and preparation method and application thereof 华中科技大学 2021-12-03 CN claimed
CN-112321782-A Crystalline covalent triazine organic framework material and preparation method and application thereof 华中科技大学 2021-02-05 CN claimed
US-10350093-B2 Degradable implantable medical devices ELIXIR MEDICAL CORPORATION (US) 2019-07-16 US claimed
CN-104146795-B Degradable implantable medical devices 万能医药公司 2017-11-10 CN claimed
EP-3225216-A1 DEGRADABLE IMPLANTABLE MEDICAL DEVICES Elixir Medical Corporation (US) 2017-10-04 EP claimed
EP-2796112-B1 Degradable implantable medical devices ELIXIR MEDICAL CORP (US) 2016-11-16 EP claimed
EP-1549247-A1 DRUG RELEASE FROM ANTITHROMBOGENIC MULTI-LAYER COATED STENT Mediplex Corporation (KR) 2005-07-06 EP claimed
EP-1539762-A2 BICYCLIC PYRIMIDINONES AS COAGULATION CASCADE INHIBITORS Bristol-Myers Squibb Company (US) 2005-06-15 EP claimed
WO-2004028406-A1 DRUG RELEASE FROM ANTITHROMBOGENIC MULTI-LAYER COATED STENT MEDIPLEX CORPORATION (KR) 2004-04-08 WO claimed
US-6702850-B1 Multi-coated drug-eluting stent for antithrombosis and antirestenosis MEDIPLEX CORPORATION KOREA (KR) 2004-03-09 US claimed
WO-2004002406-A2 BICYCLIC PYRIMIDINONES AS COAGULATION CASCADE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-01-08 WO claimed
CN-1117569-C Bicyclic fibrinogen antagonists SMITHKLINE BEECHAM CORP (US) 2003-08-13 CN claimed
US-6106866-A ANTITUMOR AGENTS AND DERMATAN SULFATE ACCESS PHARMACEUTICALS, INC. (US) 2000-08-22 US claimed
EP-0794796-A1 COMPLEXES OF DERMATAN SULFATE AND DRUGS, GIVING IMPROVED PHARMACOKINETICS Access Pharmaceuticals, Inc. (US) 1997-09-17 EP claimed
WO-1996019242-A1 COMPLEXES OF DERMATAN SULFATE AND DRUGS, GIVING IMPROVED PHARMACOKINETICS ACCESS PHARMACEUTICALS, INC. (US) 1996-06-27 WO claimed
US-5519024-A CELL ADHESION INHIBITOR TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-05-21 US claimed