SCHEMBL537030

SCHEMBL537030

N=C(N)c1ccc(C(=N)N)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.77
PLAU P00749 2/20 0.77
MASP2 O00187 1/20 0.77
THPO P40225 1/20 0.77
PRSS1 P07477 6/20 0.72
PRSS3 P35030 5/20 0.72
F2 P00734 4/20 0.72
APEX1 P27695 1/20 0.72
F10 P00742 2/20 0.71
F12 P00748 1/20 0.71
F7 P08709 1/20 0.71
F3 P13726 1/20 0.71
PKM P14618 1/20 0.71
ST14 Q9Y5Y6 3/20 0.68
PRMT1 Q99873 2/20 0.68
ALDH1A1 P00352 2/20 0.68
HPGD P15428 2/20 0.68
HSD17B10 Q99714 2/20 0.68
PRMT5 O14744 1/20 0.68
CYP2C19 P33261 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30999366 0.96 PRSS1 (0.78) LMNAPLAUMASP2THPOPRSS1
Hydrochloric Acid SCHEMBL392375 0.96 PRSS1 (0.78) LMNAPLAUMASP2THPOPRSS1
SCHEMBL8973288 0.90 WDR5 (0.80) LMNAPLAUMASP2THPOPRSS1
SCHEMBL394218 0.90 WDR5 (0.80) LMNAPLAUMASP2THPOPRSS1
Hydrochloric Acid SCHEMBL29182280 0.87 PRSS1 (0.67) LMNAPLAUMASP2THPOPRSS1
SCHEMBL6588885 0.87 LMNA (0.62) LMNAPLAUMASP2THPOPRSS1
SCHEMBL563315 0.87 LMNA (1.00) LMNAPLAUMASP2THPOPRSS1
SCHEMBL150756 0.87 PLAU (1.00) LMNAPLAUMASP2THPOPRSS1
SCHEMBL23188213 0.85 LMNA (0.59) LMNAPLAUMASP2THPOPRSS1
SCHEMBL4629405 0.85 LMNA (0.59) LMNAPLAUMASP2THPOPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119836101-A Perovskite solar cell based on diamine molten salt surface modification and preparation method thereof 东方电气长三角(杭州)创新研究院有限公司 2025-04-15 CN claimed
CN-118513038-A Hydrofining catalyst and preparation method and application thereof 中国石油化工股份有限公司 2024-08-20 CN claimed
EP-2796112-B2 Degradable implantable medical devices ELIXIR MEDICAL CORP (US) 2023-08-09 EP claimed
CN-115382576-B Covalent organic framework-bismuth tungstate photocatalytic composite material and preparation method thereof 黄石瀚海新材料科技有限公司 2023-05-16 CN claimed
CN-115382576-A Covalent organic framework-bismuth tungstate photocatalytic composite material and preparation method thereof 黄石瀚海新材料科技有限公司 2022-11-25 CN claimed
CN-115397109-A Nano graphite carbon pore process pore-finishing agent and preparation method thereof 广东利尔化学有限公司 2022-11-25 CN claimed
WO-2022217521-A1 COVALENT BOND-LINKED TIO2@CTF‑PY HETEROJUNCTION MATERIAL, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 苏州大学 2022-10-20 WO claimed
CN-112321782-B Crystalline covalent triazine organic framework material and preparation method and application thereof 华中科技大学 2021-12-03 CN claimed
CN-112321782-A Crystalline covalent triazine organic framework material and preparation method and application thereof 华中科技大学 2021-02-05 CN claimed
CN-108889334-B Application of triazine covalent organic framework material containing hetero atoms in photocatalysis 华中科技大学 2020-01-03 CN claimed
EP-2061629-A2 METHOD OF DOPING SURFACES Enbio Limited (IE) 2009-05-27 EP claimed
US-20080274671-A1 METHOD OF DOPING SURFACES ENBIO LIMITED (IE) 2008-11-06 US claimed
WO-2008033867-A2 METHOD OF DOPING SURFACES ENBIO LIMITED (IE) 2008-03-20 WO claimed
EP-1549247-A4 DRUG RELEASE FROM ANTITHROMBOGENIC MULTI-LAYER COATED STENT MEDIPLEX CORP (KR) 2007-10-31 EP claimed
EP-1549247-A1 DRUG RELEASE FROM ANTITHROMBOGENIC MULTI-LAYER COATED STENT Mediplex Corporation (KR) 2005-07-06 EP claimed
WO-2004028406-A1 DRUG RELEASE FROM ANTITHROMBOGENIC MULTI-LAYER COATED STENT MEDIPLEX CORPORATION (KR) 2004-04-08 WO claimed
US-6702850-B1 Multi-coated drug-eluting stent for antithrombosis and antirestenosis MEDIPLEX CORPORATION KOREA (KR) 2004-03-09 US claimed
US-6106866-A ANTITUMOR AGENTS AND DERMATAN SULFATE ACCESS PHARMACEUTICALS, INC. (US) 2000-08-22 US claimed
EP-0794796-A1 COMPLEXES OF DERMATAN SULFATE AND DRUGS, GIVING IMPROVED PHARMACOKINETICS Access Pharmaceuticals, Inc. (US) 1997-09-17 EP claimed
WO-1996019242-A1 COMPLEXES OF DERMATAN SULFATE AND DRUGS, GIVING IMPROVED PHARMACOKINETICS ACCESS PHARMACEUTICALS, INC. (US) 1996-06-27 WO claimed