SCHEMBL5370679

SCHEMBL5370679

CC(C=O)=CC1(C(=O)OCc2cccc(Oc3ccccc3)c2)CC1(C)C

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.51
LMNA P02545 1/20 0.48
ADRA2A P08913 1/20 0.48
CNR1 P21554 1/20 0.48
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
FFAR4 Q5NUL3 9/20 0.45
MMP1 P03956 2/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP12 P39900 1/20 0.43
FFAR1 O14842 5/20 0.40
CETP P11597 1/20 0.40
FKBP1A P62942 1/20 0.40
HTR1A P08908 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
HTR2C P28335 1/20 0.39
OPRK1 P41145 1/20 0.39
SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5370676 1.00 TDP1 (0.51) TDP1LMNAADRA2ACNR1ATM
SCHEMBL5368041 0.88 TDP1 (0.52) TDP1LMNAADRA2ACNR1ATM
SCHEMBL5368035 0.88 TDP1 (0.52) TDP1LMNAADRA2ACNR1ATM
SCHEMBL5362016 0.88 ALDH1A1 (0.46) TDP1L3MBTL1SLC6A3
SCHEMBL5362010 0.88 ALDH1A1 (0.46) TDP1L3MBTL1SLC6A3
SCHEMBL5370238 0.87 TDP1 (0.51) TDP1LMNAADRA2ACNR1ATM
SCHEMBL5370243 0.87 TDP1 (0.51) TDP1LMNAADRA2ACNR1ATM
SCHEMBL7941480 0.87 TDP1 (0.58) TDP1LMNAADRA2ACNR1ATM
SCHEMBL11467686 0.82 TDP1 (0.50) TDP1LMNAADRA2ACNR1ATM
SCHEMBL13166364 0.76 ALDH1A1 (0.50) TDP1L3MBTL1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276622-B2 Method for producing oxygen-containing compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-02 US disclosed
US-20060173221-A1 Method for producing oxygen-containing compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-03 US disclosed
EP-1609777-A1 METHOD FOR PRODUCING OXYGEN-CONTAINING COMPOUND Sumitomo Chemical Company, Limited (JP) 2005-12-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060173221-A1 Method for producing oxygen-containing compound GPX4, DUOX2, SCO2 TDP1 4530/4885LMNA 4036/4885ADRA2A 4831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.