Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | CBX7 | O95931 | 1/20 | 0.38 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.38 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454585 | 0.82 | CNR2 (0.47) | HRH3CBX7CDYL2CDYLCNR2 | |
| SCHEMBL5441664 | 0.70 | CNR2 (0.45) | CNR2ALDH1A1KDM2BKDM4E | |
| SCHEMBL5450930 | 0.70 | CNR2 (0.48) | CNR2ALDH1A1 | |
| SCHEMBL5454553 | 0.68 | HTR2A (0.47) | CNR2ALDH1A1 | |
| SCHEMBL5452683 | 0.67 | SLC6A2 (0.53) | OPRM1 | |
| SCHEMBL5446464 | 0.65 | MAPT (0.50) | CNR2ALDH1A1KDM4E | |
| SCHEMBL5454485 | 0.63 | ALOX15 (0.47) | CNR2ALDH1A1 | |
| SCHEMBL5451215 | 0.63 | ADRA1D (0.45) | CNR2 | |
| SCHEMBL14412213 | 0.63 | HTR1A (0.51) | CNR2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5448668 | 0.62 | ADRA1D (0.47) | CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079239-A2 | BICYCLIC NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-07-12 | — | — | WO | disclosed |