Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983314 | 0.82 | KDM4E (0.57) | KMT2ASMN1; SMN2RAB9AMAPTTSHR | |
| SCHEMBL2093161 | 0.82 | SMN1; SMN2 (0.65) | KMT2ASMN1; SMN2RAB9AMAPTGAA | |
| SCHEMBL23885131 | 0.81 | PDK1 (0.54) | KMT2AMAPTTSHRGAAMAPK1 | |
| SCHEMBL30254525 | 0.81 | PDK1 (0.54) | KMT2AMAPTTSHRGAAMAPK1 | |
| SCHEMBL3225418 | 0.81 | BRD4 (0.55) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL4677801 | 0.81 | LMNA (0.52) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL14337634 | 0.80 | KMT2A (0.43) | KMT2AMAPTTSHRGAAMAPK1 | |
| SCHEMBL1012748 | 0.79 | KMT2A (0.49) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL15861862 | 0.77 | FABP3 (0.50) | KMT2ASMN1; SMN2RAB9AMAPTGAA | |
| SCHEMBL16097098 | 0.77 | SMN1; SMN2 (0.48) | KMT2ACA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307098-B2 | Indole derivatives and drugs containing the same | MEIJI DAIRIES CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-20050261357-A1 | Indole derivatives and drugs containing the same | MEIJI DAIRIES CORPORATION (JP) | 2005-11-24 | — | — | US | disclosed |
| EP-1533299-A1 | INDOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | Meiji Dairies Corporation (JP) | 2005-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261357-A1 | Indole derivatives and drugs containing the same | IDO1, TPH1, IDO2 | KMT2A 1431/4885CA12 3652/4885CA1 618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.