Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4797271 | 0.78 | NPC1 (0.50) | SMN1; SMN2ALDH1A1GLATSHRHTT | |
| SCHEMBL7624337 | 0.74 | ALDH1A1 (0.47) | CYP2C19LMNAMAPK1HTR2AHRH1 | |
| SCHEMBL7701538 | 0.73 | ALDH1A1 (0.46) | ALDH1A1GLATSHRHTT | |
| SCHEMBL16296762 | 0.73 | TP53 (0.30) | ALDH1A1GLATSHR | |
| SCHEMBL4798849 | 0.72 | NPSR1 (0.52) | ALOX5CYP2C19TDP1SMN1; SMN2NPSR1 | |
| SCHEMBL16278131 | 0.71 | MLYCD (0.34) | CYP2C19SMN1; SMN2 | |
| SCHEMBL609514 | 0.70 | ALDH1A1 (0.43) | ALOX5CYP2C19PKMSMN1; SMN2NPSR1 | |
| SCHEMBL6605814 | 0.70 | TP53 (0.39) | CYP2C19DRD3DRD2SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27494938 | 0.70 | ALDH1A1 (0.47) | ALOX5CYP2C19LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4717191 | 0.69 | PARP10 (0.42) | ALOX5CYP2C19PKMSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007077333-A2 | USE OF A NEUROPEPTIDE Y ANTAGONIST FOR DAMAGED OR SENSITIVE LIPS | L'OREAL (FR) | 2007-07-12 | — | — | WO | claimed |
| WO-2007077333-A2 | USE OF A NEUROPEPTIDE Y ANTAGONIST FOR DAMAGED OR SENSITIVE LIPS | L'OREAL (FR) | 2007-07-12 | — | — | WO | disclosed |