SCHEMBL5371222

SCHEMBL5371222

OP(OCC(F)(F)C(F)(F)C(F)(F)C(F)F)OCC(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
HPGD P15428 1/20 0.38
XBP1 P17861 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 2/20 0.36
TSHR P16473 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
USP2 O75604 1/20 0.36
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP2C9 P11712 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5379019 0.92 TSHR (0.43) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL5371253 0.89 CYP1A2 (0.35) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL7576707 0.84 MAPT (0.39) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL2535309 0.83 CYP1A2 (0.37) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL6660609 0.82 TSHR (0.40) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL22710160 0.76 TSHR (0.41) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL21983907 0.75 TSHR (0.42) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL21983933 0.75 TSHR (0.42) LMNANPSR1HPGDXBP1SMN1; SMN2
SCHEMBL497555 0.75 LMNA (0.43) LMNANPSR1HPGDXBP1SMN1; SMN2
Hydrochloric Acid SCHEMBL31364520 0.73 LMNA (0.42) LMNANPSR1HPGDXBP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7285610-B2 Synthesis method for polymers by controlled radical polymerisation with xanthates RHODIA CHIMIE (FR) 2007-10-23 US disclosed
US-20050054794-A1 Synthesis method for polymers by controlled radical polymerisation with xanthates RHODIA CHIMIE (FR) 2005-03-10 US disclosed
US-6809164-B2 FORMING LOW POLYDISPERSITY MATERIALS RHODIA CHIMIE (FR) 2004-10-26 US disclosed
EP-1242467-B1 SYNTHESIS METHOD FOR POLYMERS BY CONTROLLED RADICAL POLYMERISATION WITH XANTHATES RHODIA CHIMIE SA (FR) 2004-08-11 EP disclosed
US-20030045661-A1 Synthesis method for polymers by controlled radical polymerisation with xanthates RHODIA CHIMIE (FR) 2003-03-06 US disclosed