Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660609 | 0.98 | TSHR (0.40) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL5371253 | 0.95 | CYP1A2 (0.35) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL5379019 | 0.88 | TSHR (0.43) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL5371222 | 0.84 | LMNA (0.38) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL21983907 | 0.77 | TSHR (0.42) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL21983933 | 0.77 | TSHR (0.42) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL14492286 | 0.75 | CYP1A2 (0.44) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL25979527 | 0.75 | CYP1A2 (0.44) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL25979523 | 0.75 | CYP1A2 (0.44) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL5373722 | 0.73 | POLB (0.32) | LMNAHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242467-A1 | SYNTHESIS METHOD FOR POLYMERS BY CONTROLLED RADICAL POLYMERISATION WITH XANTHATES | RHODIA CHIMIE (FR) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001042312-A1 | SYNTHESIS METHOD FOR POLYMERS BY CONTROLLED RADICAL POLYMERISATION WITH XANTHATES | RHODIA CHIMIE (FR) | 2001-06-14 | — | — | WO | disclosed |