Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371222 | 0.92 | LMNA (0.38) | TSHRMAPTUSP2CYP1A2CYP2C19 | |
| SCHEMBL6660609 | 0.90 | TSHR (0.40) | TSHRMAPTUSP2CYP1A2CYP2C19 | |
| SCHEMBL7576707 | 0.88 | MAPT (0.39) | TSHRMAPTUSP2CYP1A2CYP2C19 | |
| SCHEMBL21983933 | 0.84 | TSHR (0.42) | TSHRMAPTUSP2CYP1A2CYP2C19 | |
| SCHEMBL21983907 | 0.84 | TSHR (0.42) | TSHRMAPTUSP2CYP1A2CYP2C19 | |
| SCHEMBL5371253 | 0.81 | CYP1A2 (0.35) | TSHRMAPTUSP2CYP1A2CYP2C19 | |
| SCHEMBL11511024 | 0.77 | MAPT (0.45) | TSHRMAPTUSP2CYP1A2CYP2C19 | |
| SCHEMBL3418029 | 0.77 | MAPT (0.45) | TSHRMAPTUSP2CYP1A2CYP2C19 | |
| SCHEMBL2535309 | 0.75 | CYP1A2 (0.37) | TSHRMAPTUSP2CYP1A2CYP2C19 | |
| SCHEMBL5371455 | 0.74 | TSHR (0.35) | TSHRMAPTUSP2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285610-B2 | Synthesis method for polymers by controlled radical polymerisation with xanthates | RHODIA CHIMIE (FR) | 2007-10-23 | — | — | US | disclosed |
| US-20050054794-A1 | Synthesis method for polymers by controlled radical polymerisation with xanthates | RHODIA CHIMIE (FR) | 2005-03-10 | — | — | US | disclosed |
| US-6809164-B2 | FORMING LOW POLYDISPERSITY MATERIALS | RHODIA CHIMIE (FR) | 2004-10-26 | — | — | US | disclosed |
| EP-1242467-B1 | SYNTHESIS METHOD FOR POLYMERS BY CONTROLLED RADICAL POLYMERISATION WITH XANTHATES | RHODIA CHIMIE SA (FR) | 2004-08-11 | — | — | EP | disclosed |
| US-20030045661-A1 | Synthesis method for polymers by controlled radical polymerisation with xanthates | RHODIA CHIMIE (FR) | 2003-03-06 | — | — | US | disclosed |