SCHEMBL537149

SCHEMBL537149

CC(C)C[C@H](NC(=O)[C@@H](N)CCC(N)=O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 2/20 0.56
▸ DPP8 Q6V1X1 2/20 0.56
▸ DPP9 Q86TI2 2/20 0.56
▸ FOLH1 Q04609 7/20 0.51
▸ KMT2A Q03164 2/20 0.50
▸ ALDH1A1 P00352 2/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ BLM P54132 1/20 0.50
▸ PMP22 Q01453 1/20 0.50
▸ LAP3 P28838 3/20 0.48
▸ MEN1 O00255 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ CTSD P07339 1/20 0.45
▸ BACE1 P56817 1/20 0.45
▸ MAPT P10636 1/20 0.45
▸ LTA4H P09960 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3422138 1.00 DPP4 (0.56) DPP4DPP8DPP9FOLH1KMT2A
Leucine SCHEMBL14126315 0.96 DPP4 (0.52) DPP4DPP8DPP9FOLH1KMT2A
SCHEMBL31121653 0.94 DPP4 (0.51) DPP4DPP8DPP9FOLH1KMT2A
SCHEMBL29777822 0.94 DPP4 (0.51) DPP4DPP8DPP9FOLH1KMT2A
SCHEMBL30974319 0.93 BACE1 (0.53) DPP4DPP8DPP9FOLH1KMT2A
SCHEMBL29381184 0.93 DPP4 (0.50) DPP4DPP8DPP9FOLH1KMT2A
SCHEMBL30060796 0.93 DPP4 (0.52) DPP4DPP8DPP9FOLH1KMT2A
SCHEMBL31199055 0.92 BACE1 (0.55) DPP4DPP8DPP9FOLH1CTSD
SCHEMBL1674769 0.90 FOLH1 (0.50) DPP4DPP8DPP9FOLH1KMT2A
SCHEMBL28556186 0.89 DPP4 (0.58) DPP4DPP8DPP9FOLH1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695413-A1 PHOSPHONOALANINE OLIGOPEPTIDES AND METHODS OF MAKING AND USE THEREOF Ohio State Innovation Foundation (US) 2026-02-18 — — EP claimed
CN-118897023-B Method for directly measuring alpha and gamma-glutamyl peptide in skeletal muscle by using LC-MS and isotope dilution assay 中国农业科学院北京畜牧兽医研究所 2025-03-25 — — CN claimed
CN-119530123-A Low-sodium salt-reducing and freshness-increasing metaplasia and preparation method and application thereof 内蒙古科拓生物有限公司 2025-02-28 — — CN claimed
US-20250027938-A1 METABOLIC SIGNATURE FOR PREDICTION OF MUCOSAL INFLAMMATION AND MICROBIAL COMPOSITION IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2025-01-23 — — US claimed
CN-119291059-A Screening method for metabolic markers for distinguishing non-colorectal cancer diseases from colorectal cancer and application of screening method 哈尔滨脉图精准技术有限公司 2025-01-10 — — CN claimed
CN-118897023-A Method for directly measuring alpha and gamma-glutamyl peptide in skeletal muscle by using LC-MS and isotope dilution assay 中国农业科学院北京畜牧兽医研究所 2024-11-05 — — CN claimed
WO-2024216031-A1 PHOSPHONOALANINE OLIGOPEPTIDES AND METHODS OF MAKING AND USE THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2024-10-17 — — WO claimed
WO-2024132726-A1 SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE UNIWERSYTET GDANSKI (PL) 2024-06-27 — — WO claimed
EP-4370919-A1 METABOLIC SIGNATURE FOR PREDICTION OF MUCOSAL INFLAMMATION AND MICROBIAL COMPOSITION Imperial College Innovations Limited (GB) 2024-05-22 — — EP claimed
US-20230094471-A1 CYTOTOXIC BIS-BENZODIAZEPINE DERIVATIVES AND CONJUGATES THEREOF WITH CELL-BINDING AGENTS FOR INHIBITING ABNORMAL CELL GROWTH OR FOR TREATING PROLIFERATIVE DISEASES IMMUNOGEN, INC. (US) 2023-03-30 — — US claimed
US-20150377910-A1 Biomarkers for Fatty Liver Disease and Methods Using the Same METABOLON, INC. 2015-12-31 — — US claimed
EP-2546649-B1 Biomarkers for fatty liver disease and methods using the same METABOLON INC (US) 2015-02-25 — — EP claimed
WO-2013188333-A1 BIOMARKERS RELATED TO NEPHROTOXICITY AND METHODS USING THE SAME METABOLON, INC. (US) 2013-12-19 — — WO claimed
WO-2013155528-A2 METHODS FOR REDUCING BRAIN INFLAMMATION, INCREASING INSULIN SENSITIVITY, AND REDUCING CERAMIDE LEVELS FASGEN, INC. (US) 2013-10-17 — — WO claimed
EP-2546649-A2 Biomarkers for fatty liver disease and methods using the same Metabolon Inc. (US) 2013-01-16 — — EP claimed
EP-2227689-B1 BIOMARKERS FOR FATTY LIVER DISEASE AND METHODS USING THE SAME METABOLON INC (US) 2012-12-26 — — EP claimed
US-20100279956-A1 Biomarkers For Fatty Liver Disease And Methods Using The Same METABOLON, INC. 2010-11-04 — — US claimed
US-5863937-A PEPTIDE CONJUGATED COMPOUND AS FUNGICIDES, BACTERICIDES, MICROBIOCIDES TREATING CANDIDA ALBICANS INFECTION BTG INTERNATIONAL LIMITED (GB) 1999-01-26 — — US claimed
EP-0722456-A1 ANTIFUNGAL COMPOSITIONS BTG INTERNATIONAL LIMITED (GB) 1996-07-24 — — EP claimed
WO-1995009867-A1 ANTIFUNGAL COMPOSITIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1995-04-13 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230094471-A1 CYTOTOXIC BIS-BENZODIAZEPINE DERIVATIVES AND CONJUGATES THEREOF WITH CELL-BINDING AGENTS FOR INHIBITING ABNORMAL CELL GROWTH OR FOR TREATING PROLIFERATIVE DISEASES GABBR2, GABRB1, GABRB2 DPP4 4586/4885DPP8 4829/4885DPP9 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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