Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14529998 | 0.85 | HPGD (0.40) | HPGDTDP1HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL4462445 | 0.80 | CYP3A4 (0.50) | HPGDHSP90AA1HSP90AB1PPARAALDH1A1 | |
| SCHEMBL12590922 | 0.78 | ALDH1A1 (0.53) | HPGDHSP90AA1HSP90AB1ALDH1A1MAPT | |
| SCHEMBL4098971 | 0.78 | KDM4E (0.43) | HPGDTDP1HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL3557705 | 0.78 | MEN1 (0.41) | HPGDTDP1HSP90AA1HSP90AB1PPARA | |
| SCHEMBL4053377 | 0.76 | TSHR (0.48) | HPGDHSP90AA1HSP90AB1ALDH1A1NPC1 | |
| SCHEMBL3563407 | 0.75 | ESR1 (0.58) | HPGDHSP90AA1HSP90AB1ESR1ESR2 | |
| SCHEMBL521053 | 0.74 | KEAP1 (0.55) | HPGDTDP1HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL29956351 | 0.74 | KEAP1 (0.55) | HPGDTDP1HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL5366579 | 0.71 | PARP1 (0.41) | HPGDTDP1NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297379-B2 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-11-20 | — | — | US | disclosed |
| US-20050255258-A1 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050255258-A1 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | SCO2, CHRM1, CBR1 | LPL 4318/4885LIPG 4547/4885HPGD 3247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.