Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462445 | 0.72 | CYP3A4 (0.50) | HPGDMAPK1NPC1RAB9A | |
| SCHEMBL14052340 | 0.71 | KEAP1 (0.55) | PARP1KEAP1HPGDLMNAMAPK1 | |
| SCHEMBL5371571 | 0.71 | LPL (0.42) | HPGDLMNACNR1CNR2TDP1 | |
| SCHEMBL3557705 | 0.70 | MEN1 (0.41) | HPGDLMNAMAPK1CNR1CNR2 | |
| SCHEMBL4469757 | 0.68 | HSP90AA1 (0.45) | PARP1KEAP1HPGDMAPK1ALOX5AP | |
| SCHEMBL14529999 | 0.68 | TSHR (0.47) | PARP1KEAP1HPGDMAPK1ALOX5AP | |
| SCHEMBL9226854 | 0.68 | HTR7 (0.48) | KAT6A | |
| SCHEMBL22011230 | 0.68 | GPR3 (0.48) | RARBRARARARG | |
| SCHEMBL1599469 | 0.68 | HDAC3 (0.48) | RARBPPARGNPC1GAARAB9A | |
| SCHEMBL254969 | 0.67 | ALDH1A1 (0.56) | KEAP1HPGDLMNAMAPK1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297379-B2 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-11-20 | — | — | US | disclosed |
| US-20050255258-A1 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050255258-A1 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | SCO2, CHRM1, CBR1 | PARP1 987/4885KEAP1 2133/4885HPGD 3247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.