Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 6/20 | 0.52 |
| ▸ | NPY2R | P49146 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27722326 | 0.76 | P2RX7 (0.53) | SCDNPY2RTSHRSMN1; SMN2GBA1 | |
| SCHEMBL4262448 | 0.73 | CYP2C9 (0.63) | SCDNPY2RTSHRGBA1CYP2C9 | |
| SCHEMBL13983799 | 0.72 | SCD (0.62) | SCDNPY2RGBA1CYP2C9CYP2C19 | |
| SCHEMBL27701741 | 0.72 | SCD (0.59) | SCDNPY2RTSHRGBA1CYP2C9 | |
| SCHEMBL12894564 | 0.72 | SCD (0.59) | SCDNPY2RGBA1CYP2C9CYP2C19 | |
| SCHEMBL14172993 | 0.72 | SCD (0.59) | SCDNPY2RGBA1CYP2C9CYP2C19 | |
| SCHEMBL10304326 | 0.72 | CYP2C9 (0.60) | SCDTSHRGBA1CYP2C9CYP2C19 | |
| SCHEMBL27701738 | 0.71 | CYP2C9 (0.60) | SCDNPY2RTSHRGBA1CYP2C9 | |
| SCHEMBL4910844 | 0.71 | SCD (0.57) | SCDTSHRSMN1; SMN2GBA1USP2 | |
| SCHEMBL1781033 | 0.70 | SCD (0.52) | SCDNPY2RTSHRSMN1; SMN2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189739-B2 | Compounds and methods to treat cardiac failure and other disorders | SCIOS, INC. (US) | 2007-03-13 | — | — | US | disclosed |