Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.33 |
| ▸ | RAB9A | P51151 | 6/20 | 0.33 |
| ▸ | HTT | P42858 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | GALR3 | O60755 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536256 | 1.00 | TP53 (0.37) | TP53TBXAS1NPC1RAB9AHTT | |
| SCHEMBL7997897 | 1.00 | TP53 (0.37) | TP53TBXAS1NPC1RAB9AHTT | |
| SCHEMBL536254 | 0.97 | TP53 (0.39) | TP53TBXAS1NPC1RAB9AHTT | |
| SCHEMBL27458343 | 0.86 | TP53 (0.46) | TP53TBXAS1NPC1RAB9AHTT | |
| SCHEMBL20465806 | 0.83 | TP53 (0.48) | TP53TBXAS1NPC1RAB9AHTT | |
| SCHEMBL28164781 | 0.80 | TP53 (0.34) | TP53NPC1RAB9AHTTLMNA | |
| SCHEMBL691481 | 0.76 | TP53 (0.48) | TP53TBXAS1NPC1RAB9AHTT | |
| SCHEMBL5603811 | 0.74 | NPC1 (0.57) | TBXAS1NPC1RAB9AHTTLMNA | |
| SCHEMBL536294 | 0.74 | TP53 (0.37) | TP53TBXAS1NPC1RAB9AHTT | |
| SCHEMBL562381 | 0.74 | NPC1 (0.57) | TBXAS1NPC1RAB9AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414432-B1 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | CHEVRON ORONITE CO (US) | 2017-05-31 | — | — | EP | disclosed |
| US-9315595-B2 | Amine-terminated telechelic polymers and precursors thereto and methods for their preparation | CHEVRON ORONITE COMPANY LLC (US) | 2016-04-19 | — | — | US | disclosed |
| US-20140031497-A1 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2014-01-30 | — | — | US | disclosed |
| US-8552122-B2 | Amine-terminated telechelic polymers and precursors thereto and methods for their preparation | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2013-10-08 | — | — | US | disclosed |
| EP-2414432-A2 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | Chevron Oronite Company LLC (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010117619-A2 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | CHEVRON ORONITE COMPANY LLC (US) | 2010-10-14 | — | — | WO | disclosed |
| US-20100249001-A1 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | UNIVERSITY OF SOUTHERN MISSISSIPPI | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249001-A1 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | TERT, TELO2, TSPO | TP53 3927/4885TBXAS1 90/4885NPC1 3879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.