Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | GUSB | P08236 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 4/20 | 0.67 |
| ▸ | CA2 | P00918 | 4/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | DHFR | P00374 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347481 | 0.89 | GUSB (0.70) | ALDH1A1KDM4ETP53GUSBCA1 | |
| SCHEMBL7347477 | 0.89 | GUSB (0.70) | ALDH1A1KDM4ETP53GUSBCA1 | |
| SCHEMBL22639674 | 0.88 | GUSB (0.68) | ALDH1A1KDM4ETP53GUSBCA1 | |
| SCHEMBL22640045 | 0.88 | GUSB (0.68) | ALDH1A1KDM4ETP53GUSBCA1 | |
| SCHEMBL28567000 | 0.84 | ALDH1A1 (1.00) | ALDH1A1KDM4ETP53CA1CA2 | |
| SCHEMBL3168404 | 0.84 | CA1 (0.79) | ALDH1A1KDM4EGUSBCA1CA2 | |
| SCHEMBL14164074 | 0.84 | DHFR (0.71) | ALDH1A1KDM4ETP53GUSBCA1 | |
| SCHEMBL14164076 | 0.82 | DHFR (0.72) | ALDH1A1KDM4EGUSBCA1CA2 | |
| SCHEMBL10113599 | 0.82 | GUSB (1.00) | ALDH1A1KDM4ETP53GUSBCA1 | |
| SCHEMBL7697757 | 0.81 | CA1 (0.74) | ALDH1A1KDM4EGUSBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160449-B2 | Proline chiral columns with broad chiral selectivity | VANDERBILT UNIVERSITY (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160449-B2 | Proline chiral columns with broad chiral selectivity | VANDERBILT UNIVERSITY (US) | 2007-01-09 | — | — | US | disclosed |
| US-7141160-B2 | Chiral columns with broad chiral selectivity | V{dot over (a)}nderbilt University (US) | 2006-11-28 | — | — | US | disclosed |
| US-20050092686-A1 | Proline chiral columns with broad chiral selectivity | LI, TINGYU | 2005-05-05 | — | — | US | disclosed |
| EP-0891978-B1 | 5H-Thiazolo (3,2-a) pyrimidine derivatives | HOFFMANN LA ROCHE (CH) | 2002-03-20 | — | — | EP | disclosed |
| EP-0891978-A2 | 5H-Thiazolo (3,2-a) pyrimidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-01-20 | — | — | EP | disclosed |