SCHEMBL5372483

SCHEMBL5372483

Cc1cc(O)c(C(C)(C)C)cc1C(c1ccccc1)c1cc(C(C)(C)C)c(O)cc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 5/20 0.56
CYP2C9 P11712 4/20 0.56
TP53 P04637 3/20 0.56
CYP2C19 P33261 3/20 0.56
CYP2D6 P10635 1/20 0.56
ALDH1A1 P00352 5/20 0.45
TSHR P16473 3/20 0.45
CYP3A4 P08684 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
MAPK1 P28482 1/20 0.45
HIF1A Q16665 1/20 0.45
CYP1A2 P05177 3/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
ATP2A2 P16615 1/20 0.44
ATP2A3 Q93084 1/20 0.44
LMNA P02545 3/20 0.38
TYR P14679 3/20 0.38
HTT P42858 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278553 0.87 ALOX15 (0.53) ALOX15CYP2C9TP53CYP2C19CYP2D6
SCHEMBL9176167 0.87 ALOX15 (0.52) ALOX15CYP2C9TP53CYP2C19CYP2D6
SCHEMBL9382827 0.86 ALOX15 (0.44) ALOX15CYP2C9TP53CYP2C19CYP2D6
SCHEMBL5501277 0.84 ALOX15 (0.54) ALOX15CYP2C9TP53CYP2C19CYP2D6
SCHEMBL9670426 0.83 ALOX15 (0.60) ALOX15CYP2C9TP53CYP2C19CYP2D6
SCHEMBL9376097 0.83 ALOX15 (0.41) ALOX15CYP2C9TP53CYP2C19CYP2D6
SCHEMBL4060913 0.83 TYR (0.42) ALOX15CYP2C9CYP2C19CYP2D6ALDH1A1
SCHEMBL8814757 0.83 ALOX15 (0.51) ALOX15CYP2C9TP53CYP2C19CYP2D6
SCHEMBL5612635 0.81 ALDH1A1 (0.45) ALOX15CYP2C9TP53CYP2C19CYP2D6
SCHEMBL1238122 0.81 CYP2C9 (0.42) ALOX15CYP2C9TP53CYP2C19CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7202323-B2 Polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-04-10 US disclosed
US-20040230024-A1 Polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. 2004-11-18 US disclosed
EP-1477507-A1 Polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-11-17 EP disclosed
EP-0331095-B1 Improving stability at moderate temperatures of motor vehicle components shaped from polyvinyl chloride resin compositions WITCO CORP (US) 1996-10-09 EP disclosed
EP-0313676-B1 Bis-(2,2,6,6-tetramethyl-piperidyl) diimides as light stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO LTD (JP) 1994-01-26 EP disclosed
EP-0184203-B1 VINYL BENZYL 2,2,6,6-TETRAMETHYL PIPERIDINES ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1992-04-15 EP disclosed
EP-0188236-B1 POLYACETAL RESIN COMPOSITIONS HAVING IMPROVED RESISTANCE TO DETERIORATION WHEN EXPOSED TO LIGHT AND CONTAINING ALKYLIDENE BIS(BENZOTRIAZOLYL PHENOLS) ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1992-04-01 EP disclosed
EP-0209126-B1 HYDROCARBYL(POLYPHENOL)-POLY(2,2,6,6-TETRAMETHYL PIPERIDYL-1,3,5-TRIAZINES) AS STABILIZERS FOR SYNTHETIC POLYMER COMPOSITIONS ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1992-01-02 EP disclosed
EP-0217149-B1 POLY(2,2,6,6-TETRAMETHYLPIPERIDYLAMINOSPIROGLYCOLETHER-1,3,5-TRIAZINES) ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1991-01-30 EP disclosed
US-4957954-A TETRAMETHYPIPERIDINYL COMPOUND AND PERCHLORATE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-09-18 US disclosed
US-4146517-A FOR SYNTHETIC RESINS AGAINST HEAT ARGUS CHEMICAL CORPORATION (US) 1979-03-27 US disclosed
US-4145333-A POLYPHOSPHONATES OR PHOSPHONATE COMPOUNDS ARGUS CHEMICAL CORPORATION (US) 1979-03-20 US disclosed
US-4124564-A LIGHT AND HEAT RESISTANCE ARGUS CHEMICAL CORPORATION (US) 1978-11-07 US disclosed
US-4115476-A 2,2,6,6-Tetramethyl-4-piperidyl carbonic acid esters of dihydric alcohols and phenols as stabilizers for synthetic polymers ARGUS CHEMICAL CORPORATION (US) 1978-09-19 US disclosed
US-4107136-A Synthetic resin stabilizer comprising an organic phosphite and a carbonate ARGUS CHEMICAL CORPORATION (US) 1978-08-15 US disclosed
US-4105629-A SYNTHETIC RESIN STABILIZER COMPRISING A THIOETHER ESTER AND HINDERED PHENOLIC CARBONATE ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US disclosed
US-4105627-A MERCAPTOHETEROCYCLIC RESIN STABILIZERS ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US disclosed
US-4080364-A Stabilization of polyolefins against degradative deterioration as a result of exposure to light and air at elevated temperatures ARGUS CHEMICAL CORPORATION (US) 1978-03-21 US disclosed
US-4060513-A BENZOPHENONE U.V. STABILIZERSPOLYOLEFIN CINCINNATI MILACRON, INC. (US) 1977-11-29 US disclosed
US-3997551-A OXIDATION RESISTANCE, STABILIZE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1976-12-14 US disclosed