Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034542 | 0.88 | LMNA (0.56) | L3MBTL1 | |
| SCHEMBL3038140 | 0.85 | SMN1; SMN2 (0.47) | ALDH1A1PRMT5WDR77PTGESALOX5 | |
| SCHEMBL3045445 | 0.83 | ALOX5 (0.44) | ALDH1A1PTGESALOX5PDE4B | |
| SCHEMBL5032528 | 0.79 | KDM1A (0.51) | AMY1AALDH1A1CSNK2A1HPGDSPRMT5 | |
| SCHEMBL3047822 | 0.79 | ANO1 (0.49) | ALDH1A1L3MBTL1 | |
| SCHEMBL3051288 | 0.78 | ALDH1A1 (0.49) | ALDH1A1PTGESPDE4BL3MBTL1 | |
| SCHEMBL5035870 | 0.73 | LMNA (0.71) | L3MBTL1 | |
| SCHEMBL525597 | 0.73 | CSNK2A1 (0.65) | AMY1ACSNK2A1ALOX5L3MBTL1 | |
| SCHEMBL2324801 | 0.73 | PSEN1 (0.63) | — | |
| SCHEMBL4915995 | 0.72 | MEN1 (0.58) | ALDH1A1CSNK2A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038387-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRUSES AND CANCER | YALE UNIVERSITY (US) | 2007-04-05 | — | — | WO | disclosed |