SCHEMBL5373263

SCHEMBL5373263

OP(OCC(F)(F)C(F)F)OCC(F)(F)C(F)F

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.32
GAA P10253 1/20 0.32
TSHR P16473 1/20 0.32
ALDH1A1 P00352 2/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5373722 0.87 POLB (0.32) POLBGAAALDH1A1LMNAMAPK1
SCHEMBL20915110 0.79 MEN1 (0.32) KMT2AMEN1
SCHEMBL5371222 0.73 LMNA (0.38) TSHRLMNAMAPTTDP1KMT2A
SCHEMBL672154 0.73 HTT (0.35) HTT
SCHEMBL5379019 0.70 TSHR (0.43) TSHRLMNAMAPTTDP1KMT2A
SCHEMBL648441 0.69 MAPT (0.39) POLBALDH1A1LMNAMAPK1MAPT
SCHEMBL20971279 0.67 MEN1 (0.34) POLBALDH1A1MAPK1MAPTTDP1
SCHEMBL28891086 0.67 MEN1 (0.32) ALDH1A1KMT2AMEN1
SCHEMBL1148785 0.67 MAPT (0.39) POLBALDH1A1LMNAMAPTTDP1
SCHEMBL23054261 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7285610-B2 Synthesis method for polymers by controlled radical polymerisation with xanthates RHODIA CHIMIE (FR) 2007-10-23 US disclosed
US-20050054794-A1 Synthesis method for polymers by controlled radical polymerisation with xanthates RHODIA CHIMIE (FR) 2005-03-10 US disclosed
US-6809164-B2 FORMING LOW POLYDISPERSITY MATERIALS RHODIA CHIMIE (FR) 2004-10-26 US disclosed
EP-1242467-B1 SYNTHESIS METHOD FOR POLYMERS BY CONTROLLED RADICAL POLYMERISATION WITH XANTHATES RHODIA CHIMIE SA (FR) 2004-08-11 EP disclosed
US-20030045661-A1 Synthesis method for polymers by controlled radical polymerisation with xanthates RHODIA CHIMIE (FR) 2003-03-06 US disclosed