Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794919 | 0.92 | PARP1 (0.31) | PARP1 | |
| Monoethanolamine SCHEMBL20602874 | 0.81 | GPR84 (0.32) | — | |
| SCHEMBL6941618 | 0.70 | KDM4E (0.31) | — | |
| SCHEMBL5183774 | 0.70 | ESR1 (0.33) | — | |
| SCHEMBL4660603 | 0.69 | GPR84 (0.33) | — | |
| SCHEMBL6366338 | 0.68 | GPR84 (0.36) | — | |
| Monoethanolamine SCHEMBL28842493 | 0.67 | DAO (0.33) | — | |
| Piroctone SCHEMBL2137231 | 0.66 | KDM4E (0.44) | — | |
| Piroctone SCHEMBL2843 | 0.66 | KDM4E (0.44) | — | |
| Piroctone SCHEMBL4728215 | 0.66 | KDM4E (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768863-B1 | COSMETICS AGENTS | HENKEL KGAA (DE) | 1999-10-06 | — | — | EP | claimed |
| US-7204856-B2 | Shaped bodies for forming cosmetic preparations | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-04-17 | — | — | US | disclosed |