Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364572 | 0.85 | SMYD3 (0.37) | MAOAOPRM1OPRD1 | |
| SCHEMBL5366989 | 0.83 | CA1 (0.36) | — | |
| SCHEMBL5368717 | 0.73 | KMT2A (0.40) | OPRM1OPRD1 | |
| SCHEMBL5378282 | 0.67 | CTSL (0.42) | — | |
| SCHEMBL5371067 | 0.63 | NPC1 (0.42) | OPRD1 | |
| SCHEMBL5368051 | 0.62 | NPC1 (0.45) | — | |
| SCHEMBL5368815 | 0.62 | CA2 (0.41) | — | |
| SCHEMBL14425272 | 0.61 | LMNA (0.45) | MAOA | |
| SCHEMBL5374660 | 0.61 | LMNA (0.45) | MAOA | |
| SCHEMBL5359885 | 0.61 | SMYD3 (0.37) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259157-B2 | N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B Antagonists | MERCK & CO., INC. (US) | 2007-08-21 | — | — | US | disclosed |