Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL29016395 | 0.97 | CA2 (0.59) | CA2TSHRMEN1ALDH1A1KMT2A | |
| Sulfuric Acid SCHEMBL27733160 | 0.94 | CA2 (0.56) | CA2TSHRMEN1ALDH1A1KMT2A | |
| Sulfuric Acid SCHEMBL3785732 | 0.94 | CA2 (0.56) | CA2TSHRMEN1ALDH1A1KMT2A | |
| Potassium Ion SCHEMBL338040 | 0.94 | CA2 (0.62) | CA2TSHRMEN1ALDH1A1KMT2A | |
| Potassium Ion SCHEMBL7998268 | 0.94 | CA2 (0.62) | CA2TSHRMEN1ALDH1A1KMT2A | |
| Potassium Ion SCHEMBL8097298 | 0.94 | CA2 (0.62) | CA2TSHRMEN1ALDH1A1KMT2A | |
| Potassium Ion SCHEMBL9157649 | 0.94 | CA2 (0.62) | CA2TSHRMEN1ALDH1A1KMT2A | |
| Potassium Ion SCHEMBL8768422 | 0.94 | CA2 (0.62) | CA2TSHRMEN1ALDH1A1KMT2A | |
| Potassium Ion SCHEMBL9720346 | 0.94 | CA2 (0.62) | CA2TSHRMEN1ALDH1A1KMT2A | |
| Potassium Ion SCHEMBL10677211 | 0.94 | CA2 (0.62) | CA2TSHRMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199257-B1 | Process for the synthesis of N-(4-cyano-3-trifluoromethylphenyl)-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methylpropionamide | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-03 | — | — | US | disclosed |
| US-20070027211-A1 | Process for production of bicalutamide | APOTEX PHARMACHEM INC. | 2007-02-01 | — | — | US | disclosed |
| EP-1189898-B1 | PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULPHONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE | RICHTER GEDEON VEGYESZET (HU) | 2003-03-12 | — | — | EP | disclosed |
| EP-1189898-A1 | PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULPHONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001000608-A1 | PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULFONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2001-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027211-A1 | Process for production of bicalutamide | GABRB3, HDAC2, BLVRB | CA2 121/4885TSHR 3358/4885MEN1 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.