Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5385300 | 0.91 | LTB4R (0.47) | LTB4RLTB4R2PSEN1PTGESALOX5 | |
| SCHEMBL5377062 | 0.91 | LTB4R (0.46) | LTB4RLTB4R2PSEN1PTGESALOX5 | |
| SCHEMBL5387808 | 0.84 | FFAR1 (0.55) | PPARGMAPT | |
| SCHEMBL5383112 | 0.81 | GSTP1 (0.50) | HRH3S1PR5ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5397128 | 0.81 | GAA (0.52) | LTB4RLTB4R2HRH3L3MBTL1PSEN1 | |
| SCHEMBL6592132 | 0.81 | PTGER3 (0.51) | HRH3S1PR5ALDH1A1KDM4EGSTP1 | |
| SCHEMBL6592125 | 0.81 | PTGER3 (0.51) | HRH3S1PR5ALDH1A1KDM4EGSTP1 | |
| SCHEMBL5385882 | 0.80 | PPARG (0.47) | LTB4RLTB4R2L3MBTL1PPARGALDH1A1 | |
| SCHEMBL5374877 | 0.80 | NR1H4 (0.45) | HRH3S1PR5L3MBTL1ALOX5PPARG | |
| SCHEMBL28080889 | 0.79 | GSTP1 (0.55) | HRH3S1PR5L3MBTL1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179823-B1 | 5-membered n-heterocyclic compounds with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-20 | — | — | US | disclosed |