Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.73 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.73 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.73 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.73 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.73 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.73 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.73 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | LTA4H | P09960 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22112729 | 0.93 | HDAC1 (0.64) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL10020214 | 0.92 | HPGD (0.79) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL4171218 | 0.90 | HDAC1 (0.68) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL16128933 | 0.89 | HDAC1 (0.70) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL16128934 | 0.87 | HDAC1 (0.73) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL22015906 | 0.86 | HDAC1 (0.71) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL16128931 | 0.86 | HDAC1 (0.76) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL2120449 | 0.85 | HPGD (0.70) | HPGDKMT2ASMN1; SMN2THRATHRB | |
| SCHEMBL8411545 | 0.85 | HPGD (0.70) | HDAC1HDAC10HDAC6HDAC8HDAC2 | |
| SCHEMBL17404990 | 0.85 | HDAC1 (0.72) | HDAC1HDAC10HDAC6HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205436-B2 | Process for manufacture of quaternary ammonium tosylate salts of cinnamidoalkylamines and / or benzamidoalkylamines | GALAXY SURFACTANTS LIMITED (IN) | 2007-04-17 | — | — | US | disclosed |
| US-7147866-B2 | UV-absorbing lipid vesicles | GALAXY SURFACTANTS LIMITED (IN) | 2006-12-12 | — | — | US | disclosed |
| US-7087692-B2 | Salt and heat sensitive, substantive UV-absorbing polymers | GALAXY SURFACTANTS LTD (IN) | 2006-08-08 | — | — | US | disclosed |
| US-7045139-B2 | Process for manufacture of quaternary ammonium tosylate salts of cinnamidoalkylamines and/or benzamidoalkylamines | GALAXY SURFACTANTS LIMITED (IN) | 2006-05-16 | — | — | US | disclosed |
| US-20060067893-A1 | UV-absorbing lipid vesicles | GALAXY SURFACTANTS LIMITED (IN) | 2006-03-30 | — | — | US | disclosed |
| US-20050209327-A1 | Novel process for manufacture of quaternary ammonium tosylate salts of cinnamidoalkylamines and / or benzamidoalkylamines | GALAXY SURFACTANTS LTD. (IN) | 2005-09-22 | — | — | US | disclosed |
| US-20050080135-A1 | Novel process for manufacture of quaternary ammonium tosylate salts of cinnamidoalkylamines and/or benzamidoalkylamines | GALAXY SURFACTANTS LTD. (IN) | 2005-04-14 | — | — | US | disclosed |
| US-20040101498-A1 | Salt and heat sensitive, substantive UV-absorbing polymers | GALAXY SURFACTANTS LTD. (IN) | 2004-05-27 | — | — | US | disclosed |
| EP-0738138-A1 | QUATERNARY SALTS OF PARA-DIALKYLAMINO BENZAMIDE DERIVATIVES | ISP Van Dyk Inc. (US) | 1996-10-23 | — | — | EP | disclosed |
| EP-0738138-A4 | QUATERNARY SALTS OF PARA-DIALKYLAMINO BENZAMIDE DERIVATIVES | ISP VAN DYK INC (US) | 1996-07-08 | — | — | EP | disclosed |
| US-5451394-A | Quaternary salts of para-dialkylamino benzamide derivatives | ISP VAN DYK INC. (US) | 1995-09-19 | — | — | US | disclosed |
| US-5427773-A | Sunscreen agents | ISP VAN DYK INC. (US) | 1995-06-27 | — | — | US | disclosed |
| WO-1995005797-A1 | QUATERNARY SALTS OF PARA-DIALKYLAMINO BENZAMIDE DERIVATIVES | ISP VAN DYK INC. (US) | 1995-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040101498-A1 | Salt and heat sensitive, substantive UV-absorbing polymers | S100A10, SLC6A15, DAO | HDAC1 1790/4885HDAC10 124/4885HDAC6 1371/4885 |
| US-20050209327-A1 | Novel process for manufacture of quaternary ammonium tosylate salts of cinnamidoalkylamines and / or benzamidoalkylamines | NISCH, CUTA, PFAS | HDAC1 1160/4885HDAC10 946/4885HDAC6 659/4885 |
| US-20050080135-A1 | Novel process for manufacture of quaternary ammonium tosylate salts of cinnamidoalkylamines and/or benzamidoalkylamines | NISCH, CUTA, PFAS | HDAC1 1160/4885HDAC10 946/4885HDAC6 659/4885 |
| US-20060067893-A1 | UV-absorbing lipid vesicles | MBOAT1, ARCN1, NPC1L1 | HDAC1 492/4885HDAC10 235/4885HDAC6 929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.