⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723780 | 0.84 | ALDH1A1 (0.48) | — | |
| SCHEMBL1014097 | 0.81 | TSHR (0.43) | — | |
| SCHEMBL5044071 | 0.79 | MAPT (0.48) | — | |
| SCHEMBL9925374 | 0.79 | ALDH1A1 (0.54) | — | |
| SCHEMBL243431 | 0.79 | TSHR (0.56) | — | |
| SCHEMBL334176 | 0.79 | TSHR (0.50) | — | |
| SCHEMBL27964716 | 0.78 | TSHR (0.50) | — | |
| SCHEMBL21811856 | 0.78 | MAPT (0.52) | — | |
| SCHEMBL13625461 | 0.78 | TRPA1 (0.42) | — | |
| SCHEMBL128660 | 0.77 | TSHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589440-A | Synthesis method of methyl esculetin sodium acetate | 峰成医药科技(天津)有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-108467355-A | (R) preparation method of-Esomeprazole | 重庆润泽医药有限公司 | 2018-08-31 | — | — | CN | claimed |
| CN-105330582-B | Preparation method of (R) -4-hydroxy-2-oxo-1-pyrrolidine acetamide | 重庆润泽医药有限公司 | 2018-08-07 | — | — | CN | claimed |
| CN-106146379-B | A kind of synthetic method of Oxiracetam | 成都百途医药科技有限公司 | 2018-03-20 | — | — | CN | claimed |
| CN-106631960-A | Method for synthesizing oxiracetam | 成都百途医药科技有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-106631963-A | Oxiracetam compounding method | 成都百途医药科技有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-106631961-A | Synthetic method of oxiracetam | 成都百途医药科技有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-106478482-A | A kind of synthetic method of Oxiracetam | 成都百途医药科技有限公司 | 2017-03-08 | — | — | CN | claimed |
| CN-106349143-A | Synthetic method of oxiracetam | 成都百途医药科技有限公司 | 2017-01-25 | — | — | CN | claimed |
| CN-106349142-A | Synthetic method of oxiracetam | 成都百途医药科技有限公司 | 2017-01-25 | — | — | CN | claimed |
| CN-105330581-A | Preparation method for (S)-oxiracetam | DONGZE PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO LTD | 2016-02-17 | — | — | CN | claimed |
| CN-105330582-A | Preparation method of (R) -4-hydroxy-2-oxo-1-pyrrolidine acetamide | DONGZE PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO LTD | 2016-02-17 | — | — | CN | claimed |
| CN-104230777-A | Synthetic method of oxiracetam | CHENGDU BIOTOP PHARMA SCIENCE & TECHNOLOGY CO LTD | 2014-12-24 | — | — | CN | claimed |
| CN-102321239-B | Preparation method of water-soluble toluylene compound prodrugs | UNIV HEBEI SCIENCE & TECH | 2013-12-11 | — | — | CN | claimed |
| CN-101870769-B | PEG (Polyethylene Glycol), mPEG (Methoxy Polyethylene Glycol) chemical modifier and method thereof for preparing water-soluble resveratrol prodrug | UNIV HEBEI SCIENCE & TECH | 2012-07-25 | — | — | CN | claimed |
| CN-102321239-A | Preparation method of water-soluble toluylene compound prodrugs | UNIV HEBEI SCIENCE & TECH | 2012-01-18 | — | — | CN | claimed |
| CN-102250342-A | PEG/mPEG (Polyethylene Glycol) multi-carboxyl chemical modifying agent connected with citric acid, preparation method and application thereof in modification of toluylene compound | UNIV HEBEI SCIENCE & TECH | 2011-11-23 | — | — | CN | claimed |
| CN-101870769-A | PEG (Polyethylene Glycol), mPEG (Methoxy Polyethylene Glycol) chemical modifier and method thereof for preparing water-soluble resveratrol prodrug | HEBEI UNIVERSITY OF SCIENCE & TECHNOLOGY | 2010-10-27 | — | — | CN | claimed |
| US-5296634-A | Method for preparing 4-alkylsulfonyl-2-chloro-m-xylene | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-03-22 | — | — | US | claimed |
| EP-0481428-A1 | Method for preparing 4-alkylsulfonyl-2-chloro-M-xylene | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-04-22 | — | — | EP | claimed |