SCHEMBL5375350

SCHEMBL5375350

OB1c2ccccc2Oc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ORAI1 Q96D31 1/20 0.46
ORAI2 Q96SN7 1/20 0.46
ORAI3 Q9BRQ5 1/20 0.46
MAOA P21397 2/20 0.41
MAOB P27338 2/20 0.41
ALOX5 P09917 1/20 0.39
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
AHR P35869 3/20 0.34
P2RX4 Q99571 2/20 0.34
ATM Q13315 2/20 0.34
CA12 O43570 1/20 0.34
CA9 Q16790 1/20 0.34
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC10 Q969S8 1/20 0.32
HDAC11 Q96DB2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium SCHEMBL32675827 0.97 ORAI1 (0.44) ORAI1ORAI2ORAI3MAOAMAOB
SCHEMBL16623866 0.74 MAOA (0.39) MAOAMAOBALOX5AHRP2RX4
SCHEMBL22898110 0.74 AHR (0.39) MAOAMAOBALOX5AHRP2RX4
SCHEMBL24849506 0.74 MAOA (0.39) MAOAMAOBALOX5CA1CA2
SCHEMBL32677755 0.72 AHR (0.33) AHRP2RX4
SCHEMBL23919883 0.70 P2RX4 (0.41) MAOAMAOBALOX5P2RX4
SCHEMBL16889221 0.70 MAOA (0.36) MAOAMAOBALOX5AHRATM
SCHEMBL24631906 0.70 KDM4E (0.39) MAOAMAOBALOX5AHRATM
SCHEMBL21965189 0.70 AHR (0.37) MAOAMAOBALOX5AHRP2RX4
SCHEMBL29470906 0.70 MAOA (0.36) MAOAMAOBALOX5AHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230323029-A1 POLYMERS BASED ON IONIC MONOMERS, COMPOSITIONS COMPRISING SAME, METHODS FOR MANUFACTURING SAME, AND USE THEREOF IN ELECTROCHEMICAL APPLICATIONS HYDRO-QUéBEC (CA) 2023-10-12 US claimed
WO-2021146815-A1 POLYMERS BASED ON IONIC MONOMERS, COMPOSITIONS COMPRISING SAME, METHODS FOR MANUFACTURING SAME, AND USE THEREOF IN ELECTROCHEMICAL APPLICATIONS HYDRO-QUéBEC (CA) 2021-07-29 WO claimed
EP-3854835-A1 POLYMER COMPOSITIONS COMPRISING AT LEAST ONE POLYMER BASED ON IONIC MONOMERS, METHODS OF MAKING SAME AND THEIR USE IN ELECTROCHEMICAL APPLICATIONS HYDRO-QUEBEC (CA) 2021-07-28 EP claimed
US-20040259842-A1 Intracellular calcuim concentration increase inhibitors MIKOSHIBA, KATSUHIKO (JP) 2004-12-23 US claimed
EP-1444981-A1 INTRACELLULAR CALCIUM CONCENTRATION INCREASE INHIBITORS Mikoshiba, Katsuhiko (JP) 2004-08-11 EP claimed
US-20260052897-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-02-19 US disclosed
US-20250107441-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-03-27 US disclosed
US-12262631-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-03-25 US disclosed
US-20230323029-A1 POLYMERS BASED ON IONIC MONOMERS, COMPOSITIONS COMPRISING SAME, METHODS FOR MANUFACTURING SAME, AND USE THEREOF IN ELECTROCHEMICAL APPLICATIONS HYDRO-QUéBEC (CA) 2023-10-12 US disclosed
US-20230083954-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-03-16 US disclosed
US-20230037557-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-02-09 US disclosed
EP-4093805-A1 POLYMERS BASED ON IONIC MONOMERS, COMPOSITIONS COMPRISING SAME, METHODS FOR MANUFACTURING SAME, AND USE THEREOF IN ELECTROCHEMICAL APPLICATIONS Hydro-Québec (CA) 2022-11-30 EP disclosed
US-20180053899-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-02-22 US disclosed
US-20170213990-A1 COMPOUND AND ELECTRONIC DEVICE INCLUDING SAME SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2017-07-27 US disclosed
US-20170213990-A1 COMPOUND AND ELECTRONIC DEVICE INCLUDING SAME SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2017-07-27 US disclosed
US-7217701-B2 Intracellular calcium concentration increase inhibitors KATSUHIKO MIKOSHIBA (JP) 2007-05-15 US disclosed
US-7217701-B2 Intracellular calcium concentration increase inhibitors KATSUHIKO MIKOSHIBA (JP) 2007-05-15 US disclosed
US-7217701-B2 Intracellular calcium concentration increase inhibitors KATSUHIKO MIKOSHIBA (JP) 2007-05-15 US disclosed
US-20040259842-A1 Intracellular calcuim concentration increase inhibitors MIKOSHIBA, KATSUHIKO (JP) 2004-12-23 US disclosed
EP-1444981-A1 INTRACELLULAR CALCIUM CONCENTRATION INCREASE INHIBITORS Mikoshiba, Katsuhiko (JP) 2004-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170213990-A1 COMPOUND AND ELECTRONIC DEVICE INCLUDING SAME OR10J3, MSRB3, C1R ORAI1 2641/4885ORAI2 654/4885ORAI3 127/4885
US-20260052897-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, EED, ESRRA ORAI1 1159/4885ORAI2 468/4885ORAI3 556/4885
US-20040259842-A1 Intracellular calcuim concentration increase inhibitors CAB39, BPGM, ORAI1 ORAI1 3/4885ORAI2 41/4885ORAI3 131/4885
US-20230083954-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC ORAI1 880/4885ORAI2 224/4885ORAI3 384/4885
US-20250107441-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBPL3 ORAI1 785/4885ORAI2 70/4885ORAI3 86/4885
US-20180053899-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME OR51E2, OR10J3, ESR1 ORAI1 653/4885ORAI2 38/4885ORAI3 250/4885
US-12262631-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OTC ORAI1 880/4885ORAI2 224/4885ORAI3 384/4885
US-20230037557-A1 HETEROCYCLIC COMPOUND HCRTR2, HCRTR1, NTSR2 ORAI1 367/4885ORAI2 223/4885ORAI3 557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.