SCHEMBL537552

SCHEMBL537552

CCC1(C)CC(OC(=O)C(Cc2ccccc2)(Cc2ccccc2)C(=O)OC2CC(C)(CC)N(C)C(C)(CC)C2C)C(C)C(C)(CC)N1C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.34
PTPN2 P17706 1/20 0.34
PTPRA P18433 1/20 0.34
PTPRB P23467 1/20 0.34
CHRM2 P08172 1/20 0.33
CHRM3 P20309 1/20 0.33
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
RECQL P46063 1/20 0.32
MMP8 P22894 1/20 0.32
OPRM1 P35372 4/20 0.31
OPRD1 P41143 4/20 0.31
OPRK1 P41145 4/20 0.31
PTPRC P08575 1/20 0.31
HTR2C P28335 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11169339 0.91 KDM4E (0.30) ALDH1A1KDM4EMEN1CYP3A4MAPT
SCHEMBL7637322 0.83 HTR2C (0.35) PTPN1CYP3A4PTPRCHTR2C
SCHEMBL2036260 0.83 HTR2C (0.30) HTR2C
SCHEMBL9759942 0.81 OPRM1 (0.35) ALDH1A1KDM4EMEN1CYP3A4MAPT
SCHEMBL11534823 0.81 GAA (0.44) CHRM2CHRM3MEN1TSHRKMT2A
Benzil SCHEMBL15008957 0.77 CYP2D6 (0.37) ALDH1A1MAPTTSHRKMT2AOPRM1
SCHEMBL11532915 0.77 CTSL (0.36) OPRM1OPRD1OPRK1
SCHEMBL11169348 0.76 AMPD3 (0.30) AMPD3
SCHEMBL1902430 0.76
SCHEMBL4270589 0.76 HTR2C (0.38) ALDH1A1MEN1CYP3A4TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3365380-B1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2023-04-26 EP disclosed
US-11542389-B2 Vinyl chloride polymers and compositions for additive manufacturing AKDENIZ CHEMSON ADDITIVES AG (AT) 2023-01-03 US disclosed
US-20210017374-A1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2021-01-21 US disclosed
US-10829629-B2 Vinyl chloride polymers and compositions for additive manufacturing CHEMSON POLYMER-ADDITIVE AG (AT) 2020-11-10 US disclosed
US-10365411-B2 Hardcoat film, polarizing plate, liquid crystal display, and method for manufacturing hardcoat film FUJIFILM CORPORATION (JP) 2019-07-30 US disclosed
US-20180305536-A1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2018-10-25 US disclosed
US-9951205-B2 Stable compositions of thiabendazole and iodine-containing fungicides LANXESS DEUTSCHLAND GMBH (DE) 2018-04-24 US disclosed
US-9829606-B2 Method of manufacturing hard coat film, hard coat film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-11-28 US disclosed
US-20170322345-A1 HARDCOAT FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD FOR MANUFACTURING HARDCOAT FILM FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed
EP-2413697-B1 STABILISATION OF COMPOUNDS CONTAINING IODINE LANXESS DEUTSCHLAND GMBH (DE) 2017-11-08 EP disclosed
US-4552885-A FOR LATEX PAINTS, TETRAALKYL PYRIDINES CIBA GEIGY CORPORATION (US) 1985-11-12 US disclosed
US-4426472-A TETRAALKYLPIPERIDINES CIBA-GEIGY CORPORATION (US) 1984-01-17 US disclosed
US-4369275-A PHOTOSTABILITY FOR POLYMERS CIBA-GEIGY AG (CH) 1983-01-18 US disclosed
EP-0006213-B1 LIGHT STABILIZATION OF ACID CATALYSED STOVING ENAMELS CIBA-GEIGY AG (CH) 1982-09-01 EP disclosed
US-4315848-A PROTECTIVE COATING FOR AUTOMOBILES CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4314933-A 2,2,6,6-TETRAALKYLPIPERIDINE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1982-02-09 US disclosed
US-4293468-A Malonate derivatives as stabilizers for organic materials CIBA-GEIGY AG (CH) 1981-10-06 US disclosed
US-4278589-A 2-[2-Hydroxy-3,5-di-(α,α-dimethylbenzyl)phenyl]-2H-benzotriazole and stabilized compositions CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
US-4278590-A AUTOMOBILE FINISHES CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
EP-0006213-A1 Light stabilization of acid catalysed stoving enamels CIBA-GEIGY AG (CH) 1980-01-09 EP disclosed