Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18243918 | 0.85 | NFE2L2 (0.46) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B | |
| SCHEMBL1385780 | 0.82 | NFE2L2 (0.50) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B | |
| SCHEMBL256688 | 0.81 | NFE2L2 (0.55) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B | |
| SCHEMBL434482 | 0.79 | NFE2L2 (0.44) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B | |
| SCHEMBL27671787 | 0.78 | F7 (0.38) | NFE2L2ALDH1A1LMNAHTR2AHTR2C | |
| SCHEMBL8106391 | 0.77 | NFE2L2 (0.46) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B | |
| SCHEMBL1384058 | 0.76 | NFE2L2 (0.54) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B | |
| SCHEMBL3298105 | 0.75 | NFE2L2 (0.58) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B | |
| SCHEMBL22925060 | 0.75 | GRIN2D (0.51) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B | |
| SCHEMBL28117463 | 0.75 | PDE2A (0.49) | KDM4EHTR2AHTR2CKCNH2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104169281-B | The pyrroles's diformamide condensed and they are as the purposes of medicine | 赛诺菲 | 2016-12-14 | — | — | CN | claimed |
| CN-110358445-B | Composition for forming water-repellent film and water-repellent film | 信越化学工业株式会社 | 2022-06-17 | — | — | CN | disclosed |
| US-11118072-B2 | Water repellent film-forming composition and water repellent film | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-09-14 | — | — | US | disclosed |
| EP-3553121-B1 | WATER REPELLENT FILM-FORMING COMPOSITION AND WATER REPELLENT FILM | SHINETSU CHEMICAL CO (JP) | 2021-06-09 | — | — | EP | disclosed |
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2019-10-22 | — | — | US | disclosed |
| US-20190315972-A1 | WATER REPELLENT FILM-FORMING COMPOSITION AND WATER REPELLENT FILM | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-10-17 | — | — | US | disclosed |
| EP-3553121-A1 | WATER REPELLENT FILM-FORMING COMPOSITION AND WATER REPELLENT FILM | Shin-Etsu Chemical Co., Ltd. (JP) | 2019-10-16 | — | — | EP | disclosed |
| CN-104169281-B | The pyrroles's diformamide condensed and they are as the purposes of medicine | 赛诺菲 | 2016-12-14 | — | — | CN | disclosed |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2016-11-24 | — | — | US | disclosed |
| US-RE39531-E1 | 9-hydrazone and 9-azine erythromycin derivatives and a process for making the same | ABBOTT LABORATORIES (US) | 2007-03-27 | — | — | US | disclosed |
| WO-1999012946-A1 | 9-HYDRAZONE AND 9-AZINE ERYTHROMYCIN DERIVATIVES AND A PROCESS OF MAKING THE SAME | ABBOTT LABORATORIES (US) | 1999-03-18 | — | — | WO | disclosed |
| US-5872229-A | MULYISTAGE PROCESS OF FORMING ANTIBIOTICS BY ALKYLATION OF HYDROXY GROUPS | ABBOTT LABORATORIES (US) | 1999-02-16 | — | — | US | disclosed |
| US-5864023-A | 3'-N'oxide, 3'-n-dimethylamine, 9-oxime erythromycin a derivatives | ABBOTT LABORATORIES (US) | 1999-01-26 | — | — | US | disclosed |
| EP-0891370-A1 | 2'-PROTECTED 3'-DIMETHYLAMINE, 9-ETHEROXIME ERYTHROMYCIN A DERIVATIVES | Abbott Laboratories (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5852180-A | Chemical synthesis of 6-O-alkyl erythromycin A | ABBOTT LABORATORIES (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0874862-A2 | PROCESS FOR 6-O-ALKYLATION OF ERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1998035976-A1 | 3'-N-OXIDE, 3'-N-DIMETHYLAMINE, 9-OXIME ERYTHROMYCIN A DERIVATIVES | ABBOTT LABORATORIES (US) | 1998-08-20 | — | — | WO | disclosed |
| US-5719272-A | 2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives | ABBOTT LABORATORIES (US) | 1998-02-17 | — | — | US | disclosed |
| WO-1997036912-A1 | 2'-PROTECTED 3'-DIMETHYLAMINE, 9-ETHEROXIME ERYTHROMYCIN A DERIVATIVES | ABBOTT LABORATORIES (US) | 1997-10-09 | — | — | WO | disclosed |
| WO-1997019096-A2 | PROCESS FOR 6-O-ALKYLATION OF ERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1997-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | CBR1, HAO2, CBR3 | NFE2L2 45/4885PTGS1 758/4885PTGS2 654/4885 |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | CBR1, HAO2, CBR3 | NFE2L2 45/4885PTGS1 758/4885PTGS2 654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.