Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435684 | 0.81 | LMNA (0.34) | MAPTALDH1A1HPGDHTR2AHTR2C | |
| SCHEMBL5375815 | 0.79 | NFE2L2 (0.50) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B | |
| SCHEMBL434629 | 0.76 | NFE2L2 (0.48) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1385780 | 0.75 | NFE2L2 (0.50) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B | |
| SCHEMBL18243918 | 0.74 | NFE2L2 (0.46) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B | |
| SCHEMBL18245497 | 0.74 | NFE2L2 (0.48) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B | |
| SCHEMBL8106391 | 0.71 | NFE2L2 (0.46) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B | |
| SCHEMBL9967725 | 0.71 | NFE2L2 (0.55) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B | |
| SCHEMBL16954210 | 0.70 | NFE2L2 (0.42) | NFE2L2MAPTMEN1HPGDKMT2A | |
| SCHEMBL1384058 | 0.70 | NFE2L2 (0.54) | NFE2L2PTGS1PTGS2GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |