Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372899 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL18538369 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL18499906 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL21847561 | 0.77 | KMT2A (0.58) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL18499927 | 0.76 | MTNR1A (0.43) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL26184886 | 0.76 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTMAPK1TDP1 | |
| SCHEMBL11715074 | 0.76 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL3528800 | 0.74 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL5373055 | 0.73 | CYP11B1 (0.47) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL5379940 | 0.73 | CYP11B1 (0.51) | KDM4EALDH1A1HPGDMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170049906-A1 | TRANSLOCATION OF NON-NATURAL CHEMICAL ENTITIES THROUGH ANTHRAX PROTECTIVE ANTIGEN PORE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-02-23 | — | — | US | disclosed |
| US-9498538-B2 | Translocation of non-natural chemical entities through anthrax protective antigen pore | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-11-22 | — | — | US | disclosed |
| US-9498538-B2 | Translocation of non-natural chemical entities through anthrax protective antigen pore | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-11-22 | — | — | US | disclosed |
| US-20150165062-A1 | TRANSLOCATION OF NON-NATURAL CHEMICAL ENTITIES THROUGH ANTHRAX PROTECTIVE ANTIGEN PORE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-06-18 | — | — | US | disclosed |
| US-20150165062-A1 | TRANSLOCATION OF NON-NATURAL CHEMICAL ENTITIES THROUGH ANTHRAX PROTECTIVE ANTIGEN PORE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-06-18 | — | — | US | disclosed |
| WO-2013177231-A1 | TRANSLOCATION OF NON-NATURAL CHEMICAL ENTITIES THROUGH ANTHRAX PROTECTIVE ANTIGEN PORE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-11-28 | — | — | WO | disclosed |
| US-20070248911-A1 | Pattern forming method and bilayer film | IWASAWA HARUO | 2007-10-25 | — | — | US | disclosed |
| US-7244549-B2 | Pattern forming method and bilayer film | JSR CORPORATION (JP) | 2007-07-17 | — | — | US | disclosed |
| US-20030073040-A1 | Pattern forming method and bilayer film | JSR CORPORATION (JP) | 2003-04-17 | — | — | US | disclosed |
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |
| EP-0939754-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1998019648-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150165062-A1 | TRANSLOCATION OF NON-NATURAL CHEMICAL ENTITIES THROUGH ANTHRAX PROTECTIVE ANTIGEN PORE | ANTXR2, SLC47A2, SLC47A1 | KDM4E 4426/4885ALDH1A1 4454/4885HPGD 1200/4885 |
| US-20170049906-A1 | TRANSLOCATION OF NON-NATURAL CHEMICAL ENTITIES THROUGH ANTHRAX PROTECTIVE ANTIGEN PORE | ANTXR2, SLC47A2, SLC47A1 | KDM4E 4426/4885ALDH1A1 4454/4885HPGD 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.