Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5376093 | 0.88 | GSK3B (0.63) | GSK3BCDC7CDK2PNPPDE10A | |
| SCHEMBL5390690 | 0.83 | GSK3B (0.48) | GSK3BCDC7CCNE2CCNE1CDK2 | |
| SCHEMBL5386527 | 0.82 | GSK3B (0.53) | GSK3BCDC7CDK2PDE10AHRH3 | |
| SCHEMBL5386993 | 0.81 | GSK3B (0.48) | GSK3BCDC7 | |
| SCHEMBL5386907 | 0.81 | GSK3B (0.48) | GSK3BCDC7PDE10A | |
| SCHEMBL5375203 | 0.80 | GSK3B (0.47) | GSK3BCDC7 | |
| SCHEMBL5376074 | 0.79 | GSK3B (0.78) | GSK3BCACNA1HCDC7PDE2ACDK2 | |
| SCHEMBL5390682 | 0.78 | GSK3B (0.64) | GSK3BCDC7PDE10A | |
| SCHEMBL5380263 | 0.78 | GSK3B (0.48) | GSK3BCDC7PDE10A | |
| SCHEMBL5390451 | 0.78 | GSK3B (0.45) | GSK3BCDC7GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1115721-B1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2003-12-10 | — | — | EP | disclosed |